Literature summary extracted from
Kuhn, N.J.; Setlow, B.; Setlow, P.
Manganese(II) activation of 3-phosphoglycerate mutase of Bacillus megaterium: pH-sensitive interconversion of active and inactive forms (1993), Arch. Biochem. Biophys., 306, 342-349.
Inhibitors
EC Number |
Inhibitors |
Comment |
Organism |
Structure |
---|
5.4.2.12 |
EDTA |
complete inactivation, reactivation by Mn2+ |
Priestia megaterium |
|
Metals/Ions
EC Number |
Metals/Ions |
Comment |
Organism |
Structure |
---|
5.4.2.12 |
Mn2+ |
specific activator, none of the metal ions tested reaches more than 4% of the activity of EDTA-treated enzyme reactivated with Mn2+. Activation by Mn2+ is strongly pH-dependent within the physiological range |
Priestia megaterium |
|
5.4.2.12 |
additional information |
Cd2+, Zn2+, Fe2+, Ni2+, Cu2+, Mg2+, Ca2+, Sr2+, or Ba2+ give no more than 4% of the activity of EDTA-treated enzyme reactivated with Mn2+ |
Priestia megaterium |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
5.4.2.12 |
Priestia megaterium |
- |
- |
- |
Renatured (Commentary)
EC Number |
Renatured (Comment) |
Organism |
---|
5.4.2.12 |
reactivation of EDTA-treated enzyme by Mn2+. Several activation-deactivation cycles can be elicited |
Priestia megaterium |