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Literature summary extracted from

  • Crouch, E.A.; Cox, L.T.; Morales, K.G.; Passarelli, A.L.
    Inter-subunit interactions of the Autographa californica M nucleopolyhedrovirus RNA polymerase (2007), Virology, 367, 265-274.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.6 nucleoside triphosphate + RNAn Autographa californica M nucleopolyhedrovirus Autographa californica M nucleopolyhedrovirus transcribes genes using two DNA-directed RNA polymerases. Early genes are transcribed by the host RNA polymerase II, and late and very late genes are transcribed by a viral-encoded multisubunit RNA polymerase diphosphate + RNAn+1
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Organism

EC Number Organism UniProt Comment Textmining
2.7.7.6 Autographa californica M nucleopolyhedrovirus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.6 nucleoside triphosphate + RNAn Autographa californica M nucleopolyhedrovirus transcribes genes using two DNA-directed RNA polymerases. Early genes are transcribed by the host RNA polymerase II, and late and very late genes are transcribed by a viral-encoded multisubunit RNA polymerase Autographa californica M nucleopolyhedrovirus diphosphate + RNAn+1
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Subunits

EC Number Subunits Comment Organism
2.7.7.6 oligomer the viral RNA polymerase is composed of four proteins: Late Expression Factor-4 (LEF-4), LEF-8, LEF-9, and P47. Associations are observed between LEF-9 and P47, LEF-4 and P47, and LEF-8 and P47. LEF-4 and LEF-8 do not coimmunoprecipitate but coimmunoprecipitated in the presence of P47, suggesting that they do not associate directly. A weak association is observed between LEF-4 and LEF-9. LEF-8, LEF-9, and P47 have the ability to self-associate Autographa californica M nucleopolyhedrovirus