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Literature summary extracted from

  • Raghavenra, H.; Diwakr, B.T.; Lokesh, B.R.; Naidu, K.A.
    Eugenol--the active principle from cloves inhibits 5-lipoxygenase activity and leukotriene-C4 in human PMNL cells (2006), Prostaglandins Leukot. Essent. Fatty Acids, 74, 23-27.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.11.34 eugenol non-competitive, reversible inhibitor, IC50: 0.026 mM Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.34 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.34 leukocyte polymorphonuclear leukocyte Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.34 arachidonate + O2
-
Homo sapiens (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
-
?

Synonyms

EC Number Synonyms Comment Organism
1.13.11.34 5-LO
-
Homo sapiens

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.13.11.34 0.026
-
non-competitive, reversible inhibitor, IC50: 0.026 mM Homo sapiens eugenol