Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Poeckel, D.; Tausch, L.; Kather, N.; Jauch, J.; Werz, O.
    Boswellic acids stimulate arachidonic acid release and 12-lipoxygenase activity in human platelets independent of Ca2+ and differentially interact with platelet-type 12-lipoxygenase (2006), Mol. Pharmacol., 70, 1071-1078.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.13.11.31 beta-boswellic acid 0.03 mM, in the absence of Ca2+ Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.11.31 3-O-acetyl-11-keto-boswellic acid 0.03 mM Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.13.11.31 Ca2+ 1 mM Ca2+-dependent activity Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.31 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.31 blood platelet
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.31 arachidonate + O2
-
 Homo sapiens (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.13.11.31 12-lipoxygenase
-
 Homo sapiens
1.13.11.31 p12-LO
-
 Homo sapiens
1.13.11.31 platelet-type 12-lipoxygenase
-
 Homo sapiens