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Literature summary extracted from

  • Sheenan, P.M.; Rice, G.E.; Moses, E.K.; Brennecke, S.P.
    5beta-Dihydroprogesterone and steroid 5beta-reductase decrease in association with human parturition at term (2005), Mol. Hum. Reprod., 11, 495-501.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
1.3.99.6 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.99.6 amnion lowest expression Homo sapiens
-
1.3.99.6 blood from patients late in pregnancy, before term labour, during term labour and within the first 24 h postpartum Homo sapiens
-
1.3.99.6 chorion
-
 Homo sapiens
-
1.3.99.6 myometrium relative expression decreases significantly in association with labour by about 10fold Homo sapiens
-
1.3.99.6 placenta most highly expressed, relative expression decreases significantly in association with labour by about 2fold Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.99.6 progesterone + NADPH + H+
-
 Homo sapiens 5beta-pregnane-3,20-dione + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.99.6 steroid 5beta-reductase
-
 Homo sapiens