Literature summary extracted from

Kang, H.J.; Hong, S.M.; Kim, B.C.; Park, E.H.; Ahn, K.; Lim, C.J.
Effects of heterologous expression of thioredoxin reductase on the level of reactive oxygen species in COS-7 cells (2006), Mol. Cell, 22, 113-118.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.8.1.9	1-chloro-2,4-dinitrobenzene	0.01 mM, irreversible inhibition	Chlorocebus aethiops

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.8.1.9	Chlorocebus aethiops	-	Cercopithecus aethiops sabaeus, African green monkey	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.8.1.9	COS-7 cell	-	Chlorocebus aethiops	-
1.8.1.9	fibroblast	-	Chlorocebus aethiops	-
1.8.1.9	kidney	-	Chlorocebus aethiops	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.8.1.9	5,5'-dithiobis(2-nitrobenzoic acid) + NADPH	-	Chlorocebus aethiops	2-nitro-5-thiobenzoate + NADP+	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.8.1.9	EC 1.6.4.5	formerly	Chlorocebus aethiops
1.8.1.9	thioredoxin reductase	-	Chlorocebus aethiops
1.8.1.9	TrxR	-	Chlorocebus aethiops

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Release 2023.1 (January 2023)