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Literature summary extracted from

  • Rusten, T.E.; Rodahl, L.M.; Pattni, K.; Englund, C.; Samakovlis, C.; Dove, S.; Brech, A.; Stenmark, H.
    Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors (2006), Mol. Biol. Cell, 17, 3989-4001.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.150 ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate Drosophila sp. (in: flies) Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors. Drosophila fab1 mutants contain undetectable phosphatidylinositol 3,5-bisphosphate levels, show profound increases in cell and organ size, and die at the pupal stage ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate
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Organism

EC Number Organism UniProt Comment Textmining
2.7.1.150 Drosophila sp. (in: flies)
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.150 ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors. Drosophila fab1 mutants contain undetectable phosphatidylinositol 3,5-bisphosphate levels, show profound increases in cell and organ size, and die at the pupal stage Drosophila sp. (in: flies) ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate
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 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.150 Fab1 phosphatidylinositol 3-phosphate 5-kinase
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 Drosophila sp. (in: flies)
2.7.1.150 Fab1/PIKfyve
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 Drosophila sp. (in: flies)
2.7.1.150 PtdIns(3)P 5-kinase
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 Drosophila sp. (in: flies)