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Literature summary extracted from

  • Rodriguez-Zavala, J.S.; Ortiz-Cruz, M.A.; Moreno-Sanchez, R.
    Characterization of an aldehyde dehydrogenase from Euglena gracilis (2006), J. Eukaryot. Microbiol., 53, 36-42.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.3 Disulfiram
-
 Euglena gracilis
1.2.1.3 p-hydroxyacetophenone
-
 Euglena gracilis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.3 0.0053
-
 propanal 100 mM Na2HPO4, pH 7.4, 100 mM NaCl, 1 mM NAD+, 25°C Euglena gracilis
1.2.1.3 0.01
-
 acetaldehyde 100 mM Na2HPO4, pH 7.4, 100 mM NaCl, 1 mM NAD+, 25°C Euglena gracilis
1.2.1.3 0.047
-
 NAD+ 100 mM Na2HPO4, pH 7.4, 100 mM NaCl, 1 mM NAD+, 25°C Euglena gracilis
1.2.1.3 0.15
-
 benzaldehyde 100 mM Na2HPO4, pH 7.4, 100 mM NaCl, 1 mM NAD+, 25°C Euglena gracilis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.3 mitochondrion
-
 Euglena gracilis 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.2.1.3 Mg2+
-
 Euglena gracilis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.2.1.3 40000
-
 SDS-PAGE Euglena gracilis
1.2.1.3 160000
-
 gel-filtration Euglena gracilis

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.3 Euglena gracilis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.3 enzyme purified from the mitochondrial fraction by p-hydroxyacetophenone affinity chromatography Euglena gracilis

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.3 acetaldehyde + NAD+ + H2O
-
 Euglena gracilis acetate + NADH + H+
-
 ?
1.2.1.3 benzaldehyde + NAD+ + H2O
-
 Euglena gracilis benzoate + NADH + H+
-
 ?
1.2.1.3 propanal + NAD+ + H2O
-
 Euglena gracilis propionate + NADH
-
 ?

Subunits

EC Number Subunits Comment Organism
1.2.1.3 tetramer 4 * 40000, gel-filtration Euglena gracilis

Synonyms

EC Number Synonyms Comment Organism
1.2.1.3 aldehyde dehydrogenase
-
 Euglena gracilis
1.2.1.3 ALDH
-
 Euglena gracilis

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.2.1.3 20 35 full activity after 5 min Euglena gracilis
1.2.1.3 40
-
 50% activity after 5 min Euglena gracilis
1.2.1.3 50
-
 no activity after 5 min Euglena gracilis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.2.1.3 9.5
-
-
 Euglena gracilis

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.3 NAD+
-
 Euglena gracilis