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Literature summary extracted from

  • Philips, M.R.; Cox, A.D.
    Geranylgeranyltransferase I as a target for anti-cancer drugs (2007), J. Clin. Invest., 117, 1223-1225.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.5.1.59 medicine target for anti-cancer drugs Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.5.1.59 cytosol
-
 Mus musculus 5829
-

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.59 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.59 fibroblast
-
 Mus musculus
-
2.5.1.59 lung
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.59 geranylgeranyl diphosphate + protein-cysteine
-
 Mus musculus S-geranylgeranyl-protein + diphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.5.1.59 heterodimer
-
 Mus musculus

Synonyms

EC Number Synonyms Comment Organism
2.5.1.59 geranylgeranyltransferase type I
-
 Mus musculus
2.5.1.59 GGTase-I
-
 Mus musculus