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Literature summary extracted from

  • Liang, M.; Cai, T.; Tian, J.; Qu, W.; Xie, Z.J.
    Functional characterization of Src-interacting Na/K-ATPase using RNA interference assay (2006), J. Biol. Chem., 281, 19709-19719.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.2.2.13 Na/K ATPase-alpha1-specific siRNA A1 0% decreases in expression of human alpha subunit in 293T cells Homo sapiens
7.2.2.13 Na/K ATPase-alpha1-specific siRNA A1
-
 Sus scrofa
7.2.2.13 Na/K ATPase-alpha1-specific siRNA A2 20% decreases in expression of human alpha subunit in 293T cells Homo sapiens
7.2.2.13 Na/K ATPase-alpha1-specific siRNA A2
-
 Sus scrofa
7.2.2.13 Na/K ATPase-alpha1-specific siRNA A3 20% decreases in expression of human alpha subunit in 293T cells Homo sapiens
7.2.2.13 Na/K ATPase-alpha1-specific siRNA A3
-
 Sus scrofa
7.2.2.13 Na/K ATPase-alpha1-specific siRNA A4 40% decreases in expression of human alpha subunit in 293T cells Homo sapiens
7.2.2.13 Na/K ATPase-alpha1-specific siRNA A4
-
 Sus scrofa
7.2.2.13 Ouabain
-
 Homo sapiens
7.2.2.13 Ouabain
-
 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.2.2.13 membrane
-
 Homo sapiens 16020
-
7.2.2.13 membrane
-
 Sus scrofa 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.2.2.13 ADP + phosphate + Na+/out Homo sapiens
-
 ATP + H2O + Na+/in
-
 ?
7.2.2.13 ADP + phosphate + Na+/out Sus scrofa
-
 ATP + H2O + Na+/in
-
 ?
7.2.2.13 ATP + H2O + K+/in Homo sapiens
-
 ADP + phosphate + K+/out
-
 ?
7.2.2.13 ATP + H2O + K+/in Sus scrofa
-
 ADP + phosphate + K+/out
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.13 Homo sapiens
-
-
-
7.2.2.13 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.2.2.13 human embryonic kidney cell 293T cell Homo sapiens
-
7.2.2.13 LLC-PK1 cell
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.2.13 ADP + phosphate + Na+/out
-
 Homo sapiens ATP + H2O + Na+/in
-
 ?
7.2.2.13 ADP + phosphate + Na+/out
-
 Sus scrofa ATP + H2O + Na+/in
-
 ?
7.2.2.13 ATP + H2O + K+/in
-
 Homo sapiens ADP + phosphate + K+/out
-
 ?
7.2.2.13 ATP + H2O + K+/in
-
 Sus scrofa ADP + phosphate + K+/out
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.2.2.13 Na/K-ATPase
-
 Homo sapiens
7.2.2.13 Na/K-ATPase
-
 Sus scrofa

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
7.2.2.13 25
-
 room temperature, activity assay Homo sapiens
7.2.2.13 25
-
 room temperature, activity assay Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2.2.13 7.2
-
 activity assay Homo sapiens
7.2.2.13 7.2
-
 activity assay Sus scrofa