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Literature summary extracted from

  • Rivera, A.; Maxwell, S.A.
    The p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathway (2005), J. Biol. Chem., 280, 29346-29354.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.5.1.2 medicine mediating apoptosis in tumor cells Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.5.1.2 proline oxidase cDNA is cloned into the pAdtrack vector, it is used to generate a recombinant adenovirus for transfection Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.1.2 L-proline + NAD(P)+ Homo sapiens
-
 1-pyrroline-5-carboxylate + NAD(P)H + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.2 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.1.2 DLD-1 cell colon adenocarcinoma cell Homo sapiens
-
1.5.1.2 non-small cell lung cancer cell H1299 Homo sapiens
-
1.5.1.2 ovary cell line TOV-21G Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.2 L-proline + NAD(P)+
-
 Homo sapiens 1-pyrroline-5-carboxylate + NAD(P)H + H+
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.5.1.2 POX
-
 Homo sapiens
1.5.1.2 proline oxidase
-
 Homo sapiens
1.5.1.2 pyrroline-5-carboxylate reductase
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.1.2 NAD(P)H
-
 Homo sapiens