Literature summary extracted from

Deng, L.; Sugiura, R.; Ohta, K.; Tada, K.; Suzuki, M.; Hirata, M.; Nakamura, S.; Shuntoh, H.; Kuno, T.
Phosphatidylinositol-4-phosphate 5-kinase regulates fission yeast cell integrity through a phospholipase C-mediated protein kinase C-independent pathway (2005), J. Biol. Chem., 280, 27561-27568.

Protein Variants

EC Number	Protein Variants	Comment	Organism
2.7.1.68	additional information	mutant its3-1 shows defective PIP5K activity and sensitivity to micafungin, aculeacin A, and BE49385A	Schizosaccharomyces pombe

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.1.68	additional information	not inhibited by micafungin	Schizosaccharomyces pombe
2.7.1.68	ZnSO4	sensitive to 9 mM ZnSO4	Schizosaccharomyces pombe

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.68	Schizosaccharomyces pombe	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.1.68	ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate	-	Schizosaccharomyces pombe	ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.1.68	phosphatidylinositol-4-phosphate 5-kinase	-	Schizosaccharomyces pombe
2.7.1.68	PIP5K	-	Schizosaccharomyces pombe

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.7.1.68	ATP	-	Schizosaccharomyces pombe

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Release 2023.1 (January 2023)