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Literature summary extracted from

  • Chesneau, O.; Tsvetkova, K.; Courvalin, P.
    Resistance phenotypes conferred by macrolide phosphotransferases (2007), FEMS Microbiol. Lett., 269, 317-322.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.136 mph genes cloned into Escherichia coli AG100A Escherichia coli
2.7.1.136 mph genes cloned into Escherichia coli AG100A Salmonella enterica subsp. enterica serovar Typhimurium
2.7.1.136 mph genes cloned into Escherichia coli AG100A uncultured bacterium

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.136 Escherichia coli Q47396 plasmid pLEW517
-
2.7.1.136 Salmonella enterica subsp. enterica serovar Typhimurium Q5QJG2
-
-
2.7.1.136 uncultured bacterium A0AEF2
-
-
2.7.1.136 uncultured bacterium Q5W3B4
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.136 ATP + azithromycin the mph(A) gene conferrs resistance to azithromycin Escherichia coli ADP + azithromycin 2'-O-phosphate
-
?
2.7.1.136 ATP + azithromycin the mph(A) gene conferrs resistance to azithromycin Salmonella enterica subsp. enterica serovar Typhimurium ADP + azithromycin 2'-O-phosphate
-
?
2.7.1.136 ATP + azithromycin the mph(A) gene conferrs resistance to azithromycin uncultured bacterium ADP + azithromycin 2'-O-phosphate
-
?
2.7.1.136 ATP + telithromycin the mph(A) gene conferrs resistance to telithromycin Escherichia coli ADP + telithromycin 2'-O-phosphate
-
?
2.7.1.136 ATP + telithromycin the mph(A) gene conferrs resistance to telithromycin Salmonella enterica subsp. enterica serovar Typhimurium ADP + telithromycin 2'-O-phosphate
-
?
2.7.1.136 ATP + telithromycin the mph(A) gene conferrs resistance to telithromycin uncultured bacterium ADP + telithromycin 2'-O-phosphate
-
?