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Literature summary extracted from

  • Yasuda, S.; Kai, M.; Imai, S.; Kanoh, H.; Sakane, F.
    Diacylglycerol kinase gamma interacts with and activates beta2-chimaerin, a Rac-specific GAP, in response to epidermal growth factor (2007), FEBS Lett., 581, 551-557.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.107 expression in COS-7 cells Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
2.7.1.107 additional information heterologous expression of diacylglycerol kinase gamma in COS-7 cells. Upon stimulation with epidermal growth factor, enzyme specifically interacts and co-localizes at the plasma membrane with beta2-chimaerin. Enzyme enhances epidermal growth factor-dependent translocation of beta2-chimaerin to the plasma membrane and markedly augments epidermal growth factor-dependent GTPase-activating protein activity of beta2-chimaerin Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.107 additional information Chlorocebus aethiops diacylglycerol kinase gamma interacts with and activates beta2-chimaerin, a Rac-specific GAP, in response to epidermal growth factor ?
-
 ?
2.7.1.107 additional information Homo sapiens diacylglycerol kinase gamma regulates beta2-chimaerin, a GTPase-activating protein for Rac ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.107 Chlorocebus aethiops
-
-
-
2.7.1.107 Homo sapiens P49619
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.107 COS-7 cell
-
 Chlorocebus aethiops
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.107 additional information diacylglycerol kinase gamma interacts with and activates beta2-chimaerin, a Rac-specific GAP, in response to epidermal growth factor Chlorocebus aethiops ?
-
 ?
2.7.1.107 additional information diacylglycerol kinase gamma regulates beta2-chimaerin, a GTPase-activating protein for Rac Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.107 DGKgamma
-
 Chlorocebus aethiops