EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.1.1.13 | 1-methyl-5-amino-benzimidazole | IC50: more than 0.15 mM | Rattus norvegicus | |
2.1.1.13 | 1-methyl-5-nitro-7-methoxybenzimidazole | IC50: 0.15 mM | Rattus norvegicus | |
2.1.1.13 | 1-methyl-5-nitro-benzimidazole | IC50: more than 0.15 mM | Rattus norvegicus | |
2.1.1.13 | 1-methylbenzimidazole | IC50: more than 0.15 mM | Rattus norvegicus | |
2.1.1.13 | 2,1,3-benzothiadiazole | IC50: more than 0.15 mM | Rattus norvegicus | |
2.1.1.13 | 2-nitro-1H-benzimidazole | IC50: 0.12 mM | Rattus norvegicus | |
2.1.1.13 | 4-amino-2,1,3-benzothiadiazole | IC50: more than 0.15 mM | Rattus norvegicus | |
2.1.1.13 | 4-nitro-2,1,3-benzothiadiazole | IC50: 0.08 mM | Rattus norvegicus | |
2.1.1.13 | 5-amino-7-methoxy-N1-methylbenzimidazole | IC50: 0.095 mM | Rattus norvegicus | |
2.1.1.13 | 5-amino-7-methoxybenzimidazole | IC50: more than 0.15 mM | Rattus norvegicus | |
2.1.1.13 | 5-aminobenzimidazole | IC50: more than 0.15 mM | Rattus norvegicus | |
2.1.1.13 | 5-methoxybenzimidazole | IC50: more than 0.15 mM | Rattus norvegicus | |
2.1.1.13 | 5-nitro-7-methoxybenzimidazole | IC50: 0.1 mM | Rattus norvegicus | |
2.1.1.13 | benzimidazole | IC50: more than 0.15 mM | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.1.1.13 | 0.006 | - |
L-homocysteine | in 50 mM phosphate buffer, pH 7.4, at 37°C | Rattus norvegicus | |
2.1.1.13 | 0.025 | - |
N5-methyltetrahydropteroylmonoglutamate | in 50 mM phosphate buffer, pH 7.4, at 37°C | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.1.13 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.1.1.13 | DEAE cellulose batch chromatography and Q-sepharose column chromatography | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.1.1.13 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.13 | N5-methyltetrahydropteroylmonoglutamate + L-homocysteine | - |
Rattus norvegicus | tetrahydropteroylmonoglutamate + L-methionine | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.1.1.13 | 5-methyltetrahydrofolate-homocysteine transmethylase | - |
Rattus norvegicus |
2.1.1.13 | MetS | - |
Rattus norvegicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.1.1.13 | vitamin B12 | dependent | Rattus norvegicus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.1.1.13 | 0.017 | - |
4-nitro-2,1,3-benzothiadiazole | in 50 mM phosphate buffer, pH 7.4, at 37°C | Rattus norvegicus | |
2.1.1.13 | 0.026 | - |
2-nitro-1H-benzimidazole | in 50 mM phosphate buffer, pH 7.4, at 37°C | Rattus norvegicus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.1.1.13 | 0.08 | - |
IC50: 0.08 mM | Rattus norvegicus | 4-nitro-2,1,3-benzothiadiazole | |
2.1.1.13 | 0.095 | - |
IC50: 0.095 mM | Rattus norvegicus | 5-amino-7-methoxy-N1-methylbenzimidazole | |
2.1.1.13 | 0.1 | - |
IC50: 0.1 mM | Rattus norvegicus | 5-nitro-7-methoxybenzimidazole | |
2.1.1.13 | 0.12 | - |
IC50: 0.12 mM | Rattus norvegicus | 2-nitro-1H-benzimidazole | |
2.1.1.13 | 0.15 | - |
IC50: 0.15 mM | Rattus norvegicus | 1-methyl-5-nitro-7-methoxybenzimidazole | |
2.1.1.13 | 0.15 | - |
IC50: more than 0.15 mM | Rattus norvegicus | benzimidazole | |
2.1.1.13 | 0.15 | - |
IC50: more than 0.15 mM | Rattus norvegicus | 1-methylbenzimidazole | |
2.1.1.13 | 0.15 | - |
IC50: more than 0.15 mM | Rattus norvegicus | 5-aminobenzimidazole | |
2.1.1.13 | 0.15 | - |
IC50: more than 0.15 mM | Rattus norvegicus | 5-methoxybenzimidazole | |
2.1.1.13 | 0.15 | - |
IC50: more than 0.15 mM | Rattus norvegicus | 1-methyl-5-nitro-benzimidazole | |
2.1.1.13 | 0.15 | - |
IC50: more than 0.15 mM | Rattus norvegicus | 1-methyl-5-amino-benzimidazole | |
2.1.1.13 | 0.15 | - |
IC50: more than 0.15 mM | Rattus norvegicus | 5-amino-7-methoxybenzimidazole | |
2.1.1.13 | 0.15 | - |
IC50: more than 0.15 mM | Rattus norvegicus | 2,1,3-benzothiadiazole | |
2.1.1.13 | 0.15 | - |
IC50: more than 0.15 mM | Rattus norvegicus | 4-amino-2,1,3-benzothiadiazole |