EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
7.2.1.3 | L-galactono-gamma-lactone | - |
Mus musculus | |
7.2.1.3 | L-galactono-gamma-lactone | - |
Homo sapiens | |
7.2.1.3 | L-galactono-gamma-lactone | - |
Rattus norvegicus |
EC Number | Cloned (Comment) | Organism |
---|---|---|
7.2.1.3 | expressed in a Saccharomyces cerevisiae strain S288C DELTAfre1DELTAfre2 mutant, which lacks almost all of its plasma membrane ferrireductase activity | Mus musculus |
7.2.1.3 | expressed in a Saccharomyces cerevisiae strain S288C DELTAfre1DELTAfre2 mutant, which lacks almost all of its plasma membrane ferrireductase activity | Homo sapiens |
7.2.1.3 | expressed in a Saccharomyces cerevisiae strain S288C DELTAfre1DELTAfre2 mutant, which lacks almost all of its plasma membrane ferrireductase activity | Rattus norvegicus |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
7.2.1.3 | D38A | the mutant shows increased Fe(CN)3 reductase activity compared to the wild type enzyme | Mus musculus |
7.2.1.3 | E117A | the mutant shows decreased Fe(CN)3 reductase activity compared to the wild type enzyme | Mus musculus |
7.2.1.3 | E196A | the mutant shows decreased Fe(CN)3 reductase activity compared to the wild type enzyme | Mus musculus |
7.2.1.3 | F44A | the mutation reduces the Fe(CN)3 reductase activity by about 45% | Mus musculus |
7.2.1.3 | H105A | the mutant shows increased Fe(CN)3 reductase activity compared to the wild type enzyme | Mus musculus |
7.2.1.3 | H112A | the mutant shows decreased Fe(CN)3 reductase activity compared to the wild type enzyme | Mus musculus |
7.2.1.3 | H117A | the mutation completely abrogates the Fe(CN)3 reductase activity of the enzyme | Mus musculus |
7.2.1.3 | H156A | the mutation completely abrogates the Fe(CN)3 reductase activity of the enzyme | Mus musculus |
7.2.1.3 | H47A | the mutation completely abrogates the Fe(CN)3 reductase activity of the enzyme | Mus musculus |
7.2.1.3 | H83A | the mutation completely abrogates the Fe(CN)3 reductase activity of the enzyme | Mus musculus |
7.2.1.3 | M51A | the mutant shows increased Fe(CN)3 reductase activity compared to the wild type enzyme | Mus musculus |
7.2.1.3 | N106A | the mutant shows increased Fe(CN)3 reductase activity compared to the wild type enzyme | Mus musculus |
7.2.1.3 | P48A | the mutant shows increased reductase activity compared to the wild type enzyme | Mus musculus |
7.2.1.3 | Q131A | the activity of the mutant is reduced significantly to 45% of that of the wild type | Mus musculus |
7.2.1.3 | R149A | the mutation results in a 75% loss in activity compared to the wild type enzyme | Mus musculus |
7.2.1.3 | R67A | the mutation results in an almost complete loss of the Fe(CN)3 reductase activity | Mus musculus |
7.2.1.3 | S115A | the ferrireductase activity in the mutant is reduced to 50% | Mus musculus |
7.2.1.3 | W119A | the ferrireductase activity in the mutant is reduced to 17% | Mus musculus |
7.2.1.3 | W119A | the mutant shows decreased Fe(CN)3 reductase activity compared to the wild type enzyme | Mus musculus |
7.2.1.3 | Y190A | the mutant shows increased Fe(CN)3 reductase activity compared to the wild type enzyme | Mus musculus |
7.2.1.3 | Y66A | the mutation results in an almost complete loss of the Fe(CN)3 reductase activity | Mus musculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
7.2.1.3 | chromaffin granule | - |
Mus musculus | 42583 | - |
7.2.1.3 | chromaffin granule | - |
Homo sapiens | 42583 | - |
7.2.1.3 | chromaffin granule | - |
Rattus norvegicus | 42583 | - |
7.2.1.3 | lysosome | - |
Mus musculus | 5764 | - |
7.2.1.3 | lysosome | - |
Homo sapiens | 5764 | - |
7.2.1.3 | lysosome | - |
Rattus norvegicus | 5764 | - |
7.2.1.3 | plasma membrane | - |
Mus musculus | 5886 | - |
7.2.1.3 | plasma membrane | - |
Homo sapiens | 5886 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
7.2.1.3 | 27000 | - |
LCytb, SDS-PAGE | Mus musculus |
7.2.1.3 | 27800 | - |
CGCytb, SDS-PAGE | Mus musculus |
7.2.1.3 | 31500 | - |
DCytb, SDS-PAGE | Mus musculus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
7.2.1.3 | Homo sapiens | - |
- |
- |
7.2.1.3 | Mus musculus | - |
- |
- |
7.2.1.3 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
7.2.1.3 | duodenum | - |
Mus musculus | - |
7.2.1.3 | duodenum | - |
Homo sapiens | - |
7.2.1.3 | duodenum | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.2.1.3 | ascorbate[side 1] + Fe(CN)3[side 2] | - |
Mus musculus | monodehydroascorbate[side 1] + ? | - |
? | |
7.2.1.3 | ascorbate[side 1] + Fe(CN)3[side 2] | - |
Homo sapiens | monodehydroascorbate[side 1] + ? | - |
? | |
7.2.1.3 | ascorbate[side 1] + Fe(CN)3[side 2] | - |
Rattus norvegicus | monodehydroascorbate[side 1] + ? | - |
? | |
7.2.1.3 | ascorbate[side 1] + Fe3+-EDTA[side 2] | - |
Mus musculus | monodehydroascorbate[side 1] + ? | - |
? | |
7.2.1.3 | ascorbate[side 1] + Fe3+-EDTA[side 2] | - |
Homo sapiens | monodehydroascorbate[side 1] + ? | - |
? | |
7.2.1.3 | ascorbate[side 1] + Fe3+-EDTA[side 2] | - |
Rattus norvegicus | monodehydroascorbate[side 1] + ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
7.2.1.3 | ascorbate-dependent ferrireductase | - |
Mus musculus |
7.2.1.3 | ascorbate-dependent ferrireductase | - |
Homo sapiens |
7.2.1.3 | ascorbate-dependent ferrireductase | - |
Rattus norvegicus |
7.2.1.3 | CGCytb | - |
Mus musculus |
7.2.1.3 | CGCytb | - |
Homo sapiens |
7.2.1.3 | CGCytb | - |
Rattus norvegicus |
7.2.1.3 | chromaffin granule cytochrome b | - |
Mus musculus |
7.2.1.3 | chromaffin granule cytochrome b | - |
Homo sapiens |
7.2.1.3 | chromaffin granule cytochrome b | - |
Rattus norvegicus |
7.2.1.3 | Cyt b561 | - |
Mus musculus |
7.2.1.3 | Cyt b561 | - |
Homo sapiens |
7.2.1.3 | Cyt b561 | - |
Rattus norvegicus |
7.2.1.3 | DCytb | - |
Mus musculus |
7.2.1.3 | DCytb | - |
Homo sapiens |
7.2.1.3 | duodenal cytochrome b | - |
Mus musculus |
7.2.1.3 | duodenal cytochrome b | - |
Homo sapiens |
7.2.1.3 | LCytb | - |
Mus musculus |
7.2.1.3 | LCytb | - |
Homo sapiens |
7.2.1.3 | LCytb | - |
Rattus norvegicus |
7.2.1.3 | lysosomal cytochrome b | - |
Mus musculus |
7.2.1.3 | lysosomal cytochrome b | - |
Homo sapiens |
7.2.1.3 | lysosomal cytochrome b | - |
Rattus norvegicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
7.2.1.3 | ascorbate | dependent on | Mus musculus | |
7.2.1.3 | ascorbate | dependent on | Homo sapiens | |
7.2.1.3 | ascorbate | dependent on | Rattus norvegicus |