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Literature summary extracted from

  • Ha, Y.S.; Covert, S.F.; Momany, M.
    FsFKS1, the 1,3-beta-glucan synthase from the caspofungin-resistant fungus Fusarium solani (2006), Eukaryot. Cell, 5, 1036-1042.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.34 Caspofungin acetate IC50: 30nM Aspergillus fumigatus
2.4.1.34 Caspofungin acetate
-
 Candida albicans
2.4.1.34 additional information not inhibited by caspofungin acetate (CFA) Fusarium solani

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.34 additional information Fusarium solani cell wall biosynthetic enzyme ?
-
 ?
2.4.1.34 additional information Aspergillus fumigatus cell wall biosynthetic enzyme ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.34 Aspergillus fumigatus
-
-
-
2.4.1.34 Candida albicans
-
-
-
2.4.1.34 Fusarium solani
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.34 additional information cell wall biosynthetic enzyme Fusarium solani ?
-
 ?
2.4.1.34 additional information cell wall biosynthetic enzyme Aspergillus fumigatus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.34 beta(1,3)-D-glucan synthase
-
 Candida albicans
2.4.1.34 beta(1,3)-D-glucan synthase
-
 Fusarium solani
2.4.1.34 beta(1,3)-D-glucan synthase
-
 Aspergillus fumigatus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.4.1.34 0.00003
-
 IC50: 30nM Aspergillus fumigatus Caspofungin acetate