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Literature summary extracted from

  • Pflugmacher, S.; Wiegand, C.; Werner, S.; Schroeder, H.; Kankaanpaeae, H.
    Activity and substrate specificity of cytosolic and microsomal glutathione S-transferase in australian black tiger prawns (Penaeus monodon) after exposure to cyanobacterial toxins (2005), Environ. Toxicol., 20, 301-307.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.5.1.18 additional information low cyanobacterial toxin content was correlated with high elevation of enzymes and high toxin content with low elevation of isozymes Penaeus monodon

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.5.1.18 cytosol
-
Penaeus monodon 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.18 glutathione + microcystin-LR Penaeus monodon cyanobacterial toxins are hypothesized to contribute to the mortality of prawns, many aquatic organisms have the possibility of detoxifying cyanobacterial toxins, e.g. nodularin or microcystin-LR, via conjugation to glutathione ?
-
?
2.5.1.18 glutathione + nodularin Penaeus monodon cyanobacterial toxins are hypothesized to contribute to the mortality of prawns, many aquatic organisms have the possibility of detoxifying cyanobacterial toxins, e.g. nodularin or microcystin-LR, via conjugation to glutathione ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.18 Penaeus monodon
-
isozymes of classes mu, pi, theta, alpha, and tau
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.18 head
-
Penaeus monodon
-
2.5.1.18 hepatopancreas
-
Penaeus monodon
-
2.5.1.18 additional information isozyme-dependent tissue-specific substrate specificity, overview Penaeus monodon
-
2.5.1.18 muscle
-
Penaeus monodon
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.18 glutathione + 1,2-dichloro-4-nitrobenzene substrate of the mu class isozyme Penaeus monodon ?
-
?
2.5.1.18 glutathione + 1,2-epoxy-3-(p-nitrophenoxy)-propane substrate of the theta class isozyme Penaeus monodon ?
-
?
2.5.1.18 glutathione + 1-chloro-2,4-dinitrobenzene substrate of mu, pi, theta, alpha, and tau class isozymes Penaeus monodon chloride + 2,4-dinitrophenyl-glutathione
-
?
2.5.1.18 glutathione + 4-nitrobenzyl chloride substrate of the alpha class isozyme Penaeus monodon chloride + 4-nitrobenzyl-glutathione
-
?
2.5.1.18 glutathione + ethacrynic acid substrate of the pi class isozyme Penaeus monodon ?
-
?
2.5.1.18 glutathione + fluorodifen substrate of the tau class isozyme Penaeus monodon ?
-
?
2.5.1.18 glutathione + microcystin-LR cyanobacterial toxins are hypothesized to contribute to the mortality of prawns, many aquatic organisms have the possibility of detoxifying cyanobacterial toxins, e.g. nodularin or microcystin-LR, via conjugation to glutathione Penaeus monodon ?
-
?
2.5.1.18 glutathione + microcystin-LR a cyanobacterial toxin Penaeus monodon ?
-
?
2.5.1.18 glutathione + nodularin cyanobacterial toxins are hypothesized to contribute to the mortality of prawns, many aquatic organisms have the possibility of detoxifying cyanobacterial toxins, e.g. nodularin or microcystin-LR, via conjugation to glutathione Penaeus monodon ?
-
?
2.5.1.18 glutathione + nodularin a cyanobacterial toxin Penaeus monodon ?
-
?
2.5.1.18 additional information isozyme-dependent tissue-specific substrate specificity, overview Penaeus monodon ?
-
?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.18 glutathione S-transferase
-
Penaeus monodon
2.5.1.18 GST
-
Penaeus monodon