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Literature summary extracted from

  • Lassen, N.; Estey, T.; Tanguay, R.L.; Pappa, A.; Reimers, M.J.; Vasiliou, V.
    Molecular cloning, baculovirus expression, and tissue distribution of the zebrafish aldehyde dehydrogenase 2 (2005), Drug Metab. Dispos., 33, 649-656.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.2.1.3 2-mercaptoethanol highest activity at 50 mM Danio rerio
1.2.1.3 2-mercaptoethanol highest activity at 50 mM Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.3 expression in Spodoptera frugiperda cells Danio rerio
1.2.1.3 expression in Spodoptera frugiperda cells Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.3 0.0024
-
 propanal 0.1 M sodium diphosphate pH 8.0, 1 mM NAD+, 50 mM 2-mercaptoethanol, 1 mM pyrazole, 30 min, 25°C Homo sapiens
1.2.1.3 0.0032
-
 acetaldehyde 0.1 M sodium diphosphate pH 8.0, 1 mM NAD+, 50 mM 2-mercaptoethanol, 1 mM pyrazole, 30 min, 25°C Homo sapiens
1.2.1.3 0.0061
-
 propanal 0.1 M sodium diphosphate pH 8.0, 1 mM NAD+, 50 mM 2-mercaptoethanol, 1 mM pyrazole, 30 min, 25°C Danio rerio
1.2.1.3 0.0115
-
 acetaldehyde 0.1 M sodium diphosphate pH 8.0, 1 mM NAD+, 50 mM 2-mercaptoethanol, 1 mM pyrazole, 30 min, 25°C Danio rerio

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.2.1.3 56000
-
 SDS-PAGE Danio rerio
1.2.1.3 56000
-
 SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.3 Danio rerio
-
-
-
1.2.1.3 Homo sapiens P05091
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.3 5'-AMP-Sepharose 4B affinity column, 95% purity Danio rerio
1.2.1.3 5'-AMP-Sepharose 4B affinity column, 95% purity Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.3 brain highly expressed Danio rerio
-
1.2.1.3 eye expressed Danio rerio
-
1.2.1.3 heart highly expressed Danio rerio
-
1.2.1.3 liver expressed Danio rerio
-
1.2.1.3 skeletal muscle highly expressed Danio rerio
-
1.2.1.3 swim bladder expressed Danio rerio
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.3 acetaldehyde + NAD+ + H2O
-
 Danio rerio acetate + NADH + H+
-
 ?
1.2.1.3 acetaldehyde + NAD+ + H2O
-
 Homo sapiens acetate + NADH + H+
-
 ?
1.2.1.3 propanal + NAD+ + H2O
-
 Danio rerio propionate + NADH
-
 ?
1.2.1.3 propanal + NAD+ + H2O
-
 Homo sapiens propionate + NADH
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.3 aldehyde dehydrogenase
-
 Danio rerio
1.2.1.3 aldehyde dehydrogenase
-
 Homo sapiens
1.2.1.3 ALDH2
-
 Danio rerio
1.2.1.3 ALDH2
-
 Homo sapiens