EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.7.1.74 | cytoplasm | - |
Homo sapiens | 5737 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.74 | NTP + 2',2'-difluorodeoxycytidine | Homo sapiens | i.e. gemcitabine, rate limiting enzyme in the activation of the pharmaceutically relevant substrate which is commonly used in the treatment of solid malignant tumors | NDP + 2',2'-difluorodeoxycytidine 5'-phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.74 | Homo sapiens | - |
patients suffering from pancreatic cancer, survival of patients is found to be correlated to the detected enzyme level | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.74 | AsPC-1 cell | - |
Homo sapiens | - |
2.7.1.74 | BxPC3 cell | - |
Homo sapiens | - |
2.7.1.74 | CAPAN-1 cell | - |
Homo sapiens | - |
2.7.1.74 | CAPAN-2 cell | - |
Homo sapiens | - |
2.7.1.74 | CFPAC cell | - |
Homo sapiens | - |
2.7.1.74 | HS578 cell | - |
Homo sapiens | - |
2.7.1.74 | HS766T cell | - |
Homo sapiens | - |
2.7.1.74 | MiaPaCa-2 cell | - |
Homo sapiens | - |
2.7.1.74 | PANC-1 cell | - |
Homo sapiens | - |
2.7.1.74 | pancreas | pancreatic cancer tissue, enzyme detected in 40 out of 44 patient samples | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.74 | NTP + 2',2'-difluorodeoxycytidine | i.e. gemcitabine, rate limiting enzyme in the activation of the pharmaceutically relevant substrate which is commonly used in the treatment of solid malignant tumors | Homo sapiens | NDP + 2',2'-difluorodeoxycytidine 5'-phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.74 | dCK | - |
Homo sapiens |