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Literature summary extracted from

  • Gao, S.; von Schumann, G.; Stoeckigt, J.
    Biosynthesis of monoterpenoid indole alkaloid ajmaline catalyzed by novel reductases (2006), Chem. Res. Chin. Univ., 22, 267-269.
No PubMed abstract available

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.3.1.73 49000
-
-
 Rauvolfia serpentina
1.5.1.32 43000
-
 determined by SDS-PAGE Rauvolfia serpentina

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.73 17-O-acetylnorajmaline + NADP+ Rauvolfia serpentina
-
 1,2-dihydrovomilenine + NADPH + H+
-
 r
1.5.1.32 1,2-dihydrovomilenine + NADP+ Rauvolfia serpentina
-
 vomilenine + NADPH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.73 Rauvolfia serpentina
-
-
-
1.5.1.32 Rauvolfia serpentina
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.5.1.32 enzyme extract is obtained by crushing the cells, followed by filtration, centrifugation and ammonium precipitation Rauvolfia serpentina

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.73 17-O-acetylnorajmaline + NADP+
-
 Rauvolfia serpentina 1,2-dihydrovomilenine + NADPH + H+
-
 r
1.5.1.32 1,2-dihydrovomilenine + NADP+
-
 Rauvolfia serpentina vomilenine + NADPH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.73 1,2-dihydrovomilenine reductase
-
 Rauvolfia serpentina
1.5.1.32 vomilenine reductase
-
 Rauvolfia serpentina

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.73 NADP+
-
 Rauvolfia serpentina
1.3.1.73 NADPH
-
 Rauvolfia serpentina
1.5.1.32 NADPH
-
 Rauvolfia serpentina