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Literature summary extracted from

  • Hanioka, N.; Takeda, Y.; Jinno, H.; Tanaka-Kagawa, T.; Naito, S.; Koeda, A.; Shimizu, T.; Nomura, M.; Narimatsu, S.
    Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A6 enzymes (2006), Chem. Biol. Interact., 164, 136-145.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.17 heterologously expression in Saccharomyces cerevisiae Macaca fascicularis
2.4.1.17 heterologously expression in Saccharomyces cerevisiae Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.17 0.108
-
 4-Methylumbelliferone 37°C, pH 7.4 Homo sapiens
2.4.1.17 0.206
-
 4-Methylumbelliferone 37°C, pH 7.4 Macaca fascicularis
2.4.1.17 5.73
-
 serotonin 37°C, pH 7.4 Macaca fascicularis
2.4.1.17 8.6
-
 serotonin 37°C, pH 7.4 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.17 microsome
-
 Macaca fascicularis
-
-
2.4.1.17 microsome
-
 Homo sapiens
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.17 Homo sapiens P19224
-
-
2.4.1.17 Macaca fascicularis
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.17 liver
-
 Macaca fascicularis
-
2.4.1.17 liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.17 4-methylumbelliferone + UDP-glucuronate
-
 Macaca fascicularis UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide
-
 ?
2.4.1.17 4-methylumbelliferone + UDP-glucuronate
-
 Homo sapiens UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide
-
 ?
2.4.1.17 UDP-glucuronate + serotonin
-
 Macaca fascicularis ?
-
 ?
2.4.1.17 UDP-glucuronate + serotonin
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.17 monUGT1A6
-
 Macaca fascicularis
2.4.1.17 UDP-glucuronosyltransferase 1A6
-
 Macaca fascicularis
2.4.1.17 UDP-glucuronosyltransferase 1A6
-
 Homo sapiens
2.4.1.17 UGT1A6
-
 Homo sapiens