Literature summary extracted from

Wojtas, M.; Swiezewski, S.; Sarnowski, T.J.; Plochocka, D.; Chelstowska, A.; Tolmachova, T.; Swiezewska, E.
Cloning and characterization of Rab Escort Protein (REP) from Arabidopsis thaliana (2007), Cell Biol. Int., 31, 246-251.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.5.1.60	geranylgeranyl diphosphate + Rab protein	Arabidopsis thaliana	intracellular vesicular trafficking is regulated by Rab proteins, small GTPases that require posttranslational geranylgeranylation for biological activity, which is catalyzed by the enzyme, a Rab geranylgeranyl transferase together with the Rab escort protein, REP, overview	S-geranylgeranyl-Rab protein + diphosphate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.60	Arabidopsis thaliana	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.5.1.60	geranylgeranyl diphosphate + Rab protein	-	Arabidopsis thaliana	S-geranylgeranyl-Rab protein + diphosphate	-	?
2.5.1.60	geranylgeranyl diphosphate + Rab protein	intracellular vesicular trafficking is regulated by Rab proteins, small GTPases that require posttranslational geranylgeranylation for biological activity, which is catalyzed by the enzyme, a Rab geranylgeranyl transferase together with the Rab escort protein, REP, overview	Arabidopsis thaliana	S-geranylgeranyl-Rab protein + diphosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.5.1.60	Rab geranylgeranyl transferase	-	Arabidopsis thaliana
2.5.1.60	RabGGTase	-	Arabidopsis thaliana

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.5.1.60	additional information	the enzyme is absolutely dependent on the Rab escort protein, REP, cloning and expression of His-tagged REP in Escherichia coli, and purification, overview	Arabidopsis thaliana

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Release 2023.1 (January 2023)