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Literature summary extracted from

  • Mehdi, M.Z.; Azar, Z.M.; Srivastava, A.K.
    Role of receptor and nonreceptor protein tyrosine kinases in H2O2-induced PKB and ERK1/2 signaling (2007), Cell Biochem. Biophys., 47, 1-10.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.10.1 hydrogen peroxide
-
 Homo sapiens
2.7.10.1 reactive oxygen species
-
 Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.10.1 3-bromo-5-t-butyl-4-hydroxy-benzylidenemalonitrile
-
 Sus scrofa
2.7.10.1 4-(3-chloroanilino)-6,7-dimethoxyquinazoline
-
 Homo sapiens
2.7.10.1 4-amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine
-
 Homo sapiens
2.7.10.1 4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine
-
 Homo sapiens
2.7.10.1 6,7-dimethyl-2-phenylquinoxaline
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.7.10.1 Homo sapiens
-
-
-
2.7.10.1 Rattus norvegicus
-
-
-
2.7.10.1 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.10.1 epithelium
-
 Homo sapiens
-
2.7.10.1 fibroblast
-
 Rattus norvegicus
-
2.7.10.1 heart
-
 Sus scrofa
-
2.7.10.1 mesenteric artery
-
 Homo sapiens
-
2.7.10.1 muscle
-
 Homo sapiens
-
2.7.10.1 smooth muscle
-
 Sus scrofa
-
2.7.10.1 thoracic aorta
-
 Rattus norvegicus
-
2.7.10.1 vascular smooth muscle cell
-
 Homo sapiens
-

Synonyms

EC Number Synonyms Comment Organism
2.7.10.1 C-SRC
-
 Homo sapiens
2.7.10.1 Egfr
-
 Homo sapiens
2.7.10.1 epidermal growth factor receptor kinase
-
 Homo sapiens
2.7.10.1 IGF-1R
-
 Sus scrofa
2.7.10.1 insulin-like growth factor-1 receptor kinase
-
 Sus scrofa
2.7.10.1 PDGF receptor
-
 Rattus norvegicus
2.7.10.1 PDGFR
-
 Rattus norvegicus
2.7.10.1 platelet-derived growth factor receptor kinase
-
 Rattus norvegicus
2.7.10.1 proline-rich tyrosinekinase
-
 Homo sapiens
2.7.10.1 Pyk-2
-
 Homo sapiens