EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.74 | NTP + 2',2'-difluorodeoxycytidine | Homo sapiens | i.e. gemcitabine, rate limiting enzyme in the activation of the pharmaceutically relevant substrate which is commonly used in the treatment of tumors | NDP + 2',2'-difluorodeoxycytidine 5'-phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.74 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.74 | A-549 cell | - |
Homo sapiens | - |
2.7.1.74 | CAL-27 cell | lowest specific activity among the cell lines used | Homo sapiens | - |
2.7.1.74 | ECV304 cell | highest specific activity among the cell lines used | Homo sapiens | - |
2.7.1.74 | FaDu cell | - |
Homo sapiens | - |
2.7.1.74 | H292 cell | - |
Homo sapiens | - |
2.7.1.74 | HT-29 cell | - |
Homo sapiens | - |
2.7.1.74 | MCF-7 cell | - |
Homo sapiens | - |
2.7.1.74 | PANC-1 cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.74 | NTP + 2',2'-difluorodeoxycytidine | i.e. gemcitabine, rate limiting enzyme in the activation of the pharmaceutically relevant substrate which is commonly used in the treatment of tumors | Homo sapiens | NDP + 2',2'-difluorodeoxycytidine 5'-phosphate | - |
? | |
2.7.1.74 | NTP + 2-chloro-2'-deoxyadenosine | - |
Homo sapiens | NDP + 2-chloro-2'-deoxyadenosine 5'-phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.74 | dCK | - |
Homo sapiens |