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Literature summary extracted from

  • Winnall, W.R.; Ali, U.; Obryan, M.K.; Hirst, J.J.; Whiley, P.A.; Muir, J.A.; Hedger, M.P.
    Constitutive expression of prostaglandin-endoperoxide synthase 2 by somatic and spermatogenic cells is responsible for prostaglandin E2 production in the adult rat testis (2007), Biol. Reprod., 76, 759-768.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.99.1 NS-398
-
Rattus norvegicus
1.14.99.1 valeryl salicylate
-
Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.99.1 arachidonate + AH2 + O2 Rattus norvegicus
-
prostaglandin H2 + A + H2O
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.14.99.1 Rattus norvegicus
-
Sprague-Dawley rat
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.99.1 adrenal gland
-
Rattus norvegicus
-
1.14.99.1 brain cortex
-
Rattus norvegicus
-
1.14.99.1 epididymis caput and cauda Rattus norvegicus
-
1.14.99.1 liver
-
Rattus norvegicus
-
1.14.99.1 lung
-
Rattus norvegicus
-
1.14.99.1 prostate gland anterior prostate Rattus norvegicus
-
1.14.99.1 renal cortex
-
Rattus norvegicus
-
1.14.99.1 testis somatic and spermatogenic cells Rattus norvegicus
-
1.14.99.1 vas deferens
-
Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.99.1 arachidonate + AH2 + O2
-
Rattus norvegicus prostaglandin H2 + A + H2O
-
?

Synonyms

EC Number Synonyms Comment Organism
1.14.99.1 prostaglandin-endoperoxide synthase 1
-
Rattus norvegicus
1.14.99.1 prostaglandin-endoperoxide synthase 2
-
Rattus norvegicus
1.14.99.1 PTGS1
-
Rattus norvegicus
1.14.99.1 PTGS2
-
Rattus norvegicus