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Literature summary extracted from

  • Novak, P.; Krofta, K.; Matousek, J.
    Chalcone synthase homologues from Humulus lupulus: some enzymatic properties and expression (2006), Biol. Plant., 50, 48-54.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.74 expression in Escherichia coi. Humulus lupulus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.74 0.008
-
 isovaleryl-CoA
-
 Humulus lupulus
2.3.1.74 0.0149
-
 isobutyryl-CoA
-
 Humulus lupulus
2.3.1.74 0.0409
-
 4-coumaroyl-CoA
-
 Humulus lupulus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.74 4-coumaroyl-CoA + 3 malonyl-CoA Humulus lupulus key enzyme in prenylflavonoid biosynthesis naringenin chalcone + 4 CoA + 3 CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.74 Humulus lupulus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.74 4-coumaroyl-CoA + 3 malonyl-CoA
-
 Humulus lupulus naringenin chalcone + 4 CoA + 3 CO2
-
 ?
2.3.1.74 4-coumaroyl-CoA + 3 malonyl-CoA key enzyme in prenylflavonoid biosynthesis Humulus lupulus naringenin chalcone + 4 CoA + 3 CO2
-
 ?
2.3.1.74 isobutyryl-CoA + malonyl-CoA
-
 Humulus lupulus ?
-
 ?
2.3.1.74 isovaleryl-CoA + malonyl-CoA
-
 Humulus lupulus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.74 CHS_H1
-
 Humulus lupulus