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Literature summary extracted from

  • Nickel, C.; Trujillo, M.; Rahlfs, S.; Deponte, M.; Radi, R.; Becker, K.
    Plasmodium falciparum 2-Cys peroxiredoxin reacts with plasmoredoxin and peroxynitrite (2005), Biol. Chem., 386, 1129-1136.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
1.11.1.24 C170A kcat/Km of mutant enzyme is reduced for thioredoxin as a substrate approximately 50fold. In contrast to the wildtype enzyme, covalently linked dimers are not formed Plasmodium falciparum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.11.1.24 additional information
-
 additional information
-
 Plasmodium falciparum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.11.1.24 additional information Plasmodium falciparum the enzyme is involved in the detoxification of reactive oxygen species and of reactive nitrogen species ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.24 Plasmodium falciparum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.24 H2O2 + reduced plasmoredoxin
-
 Plasmodium falciparum H2O + oxidized plasmoredoxin
-
 ?
1.11.1.24 H2O2 + reduced thioredoxin
-
 Plasmodium falciparum H2O + oxidized thioredoxin
-
 ?
1.11.1.24 additional information the enzyme is involved in the detoxification of reactive oxygen species and of reactive nitrogen species Plasmodium falciparum ?
-
 ?
1.11.1.24 additional information PfTPx1 also possesses peroxynitrite reductase activity Plasmodium falciparum ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.11.1.24 dimer
-
 Plasmodium falciparum

Synonyms

EC Number Synonyms Comment Organism
1.11.1.24 2-Cys peroxiredoxin
-
 Plasmodium falciparum
1.11.1.24 TPx1
-
 Plasmodium falciparum