Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • De Jong, H.; Neal, A.C.; Coleman, R.A.; Lewin, T.M.
    Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart (2007), Biochim. Biophys. Acta, 1771, 75-82.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.2.1.3 arachidonate inhibits palmitoyl-CoA synthesis at high concentrations Mus musculus
6.2.1.3 additional information not inhibited by thiazolidinediones; not inhibited by thiazolidinediones; not inhibited by triacsin C; not inhibited by triacsin C; not inhibited by triacsin C Mus musculus
6.2.1.3 thiazolidinediones
-
 Mus musculus
6.2.1.3 Triacsin C
-
 Mus musculus
6.2.1.3 troglitazone 0.05 mM, 5% inhibition Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.3 Mus musculus P41216
-
-
6.2.1.3 Mus musculus Q8JZR0
-
-
6.2.1.3 Mus musculus Q91WC3
-
-
6.2.1.3 Mus musculus Q9CZW4
-
-
6.2.1.3 Mus musculus Q9QUJ7
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.2.1.3 heart
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.3 ATP + arachidonate + CoA
-
 Mus musculus AMP + diphosphate + arachidonoyl-CoA
-
 ?
6.2.1.3 ATP + eicosapentaenoate + CoA
-
 Mus musculus AMP + diphosphate + eicosapentaenoyl-CoA
-
 ?
6.2.1.3 ATP + laurate + CoA
-
 Mus musculus AMP + diphosphate + lauroyl-CoA
-
 ?
6.2.1.3 ATP + myristate + CoA
-
 Mus musculus AMP + diphosphate + myristoyl-CoA
-
 ?
6.2.1.3 ATP + palmitate + CoA
-
 Mus musculus AMP + diphosphate + palmitoyl-CoA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.2.1.3 ACSL1
-
 Mus musculus
6.2.1.3 ACSL3
-
 Mus musculus
6.2.1.3 ACSL4
-
 Mus musculus
6.2.1.3 ACSL5
-
 Mus musculus
6.2.1.3 ACSL6
-
 Mus musculus
6.2.1.3 long-chain acyl-CoA synthetase
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
6.2.1.3 ATP
-
 Mus musculus