EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.43 | apolipoprotein A-I | activation level depends on the substrate, overview | Mus musculus | |
2.3.1.43 | apolipoprotein E | activation level depends on the substrate, overview | Mus musculus |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.43 | expression of C-terminally His6-tagged LCAT in CHO cells | Mus musculus |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.3.1.43 | additional information | mice deficient in apo A-I and especially in apoE lipoproteins show reduced plasma enzyme activity, overview | Mus musculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.3.1.43 | extracellular | - |
Mus musculus | - |
- |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.43 | phosphatidylcholine + cholesterol | Mus musculus | LCAT contributes significantly to the apoB lipoprotein cholesteryl ester pool, enzyme role in lipid and lipoprotein metabolism in plasma, detailed overview | 1-acylglycerophosphocholine + cholesteryl ester | - |
? | |
2.3.1.43 | phosphatidylcholine + cholesterol | Mus musculus C57BL/6 | LCAT contributes significantly to the apoB lipoprotein cholesteryl ester pool, enzyme role in lipid and lipoprotein metabolism in plasma, detailed overview | 1-acylglycerophosphocholine + cholesteryl ester | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.43 | Mus musculus | - |
C57BL/6 mice | - |
2.3.1.43 | Mus musculus C57BL/6 | - |
C57BL/6 mice | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.1.43 | plasma | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.43 | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine + cholesterol | in presence of apoA-I lipoprotein | Mus musculus | 1-palmitoyl-sn-glycero-3-phosphocholine + cholesteryl oleate | - |
? | |
2.3.1.43 | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine + cholesterol | in presence of apoA-I lipoprotein | Mus musculus C57BL/6 | 1-palmitoyl-sn-glycero-3-phosphocholine + cholesteryl oleate | - |
? | |
2.3.1.43 | phosphatidylcholine + cholesterol | LCAT contributes significantly to the apoB lipoprotein cholesteryl ester pool, enzyme role in lipid and lipoprotein metabolism in plasma, detailed overview | Mus musculus | 1-acylglycerophosphocholine + cholesteryl ester | - |
? | |
2.3.1.43 | phosphatidylcholine + cholesterol | activity with apoB lipoprotein, overview | Mus musculus | 1-acylglycerophosphocholine + cholesteryl ester | - |
? | |
2.3.1.43 | phosphatidylcholine + cholesterol | LCAT contributes significantly to the apoB lipoprotein cholesteryl ester pool, enzyme role in lipid and lipoprotein metabolism in plasma, detailed overview | Mus musculus C57BL/6 | 1-acylglycerophosphocholine + cholesteryl ester | - |
? | |
2.3.1.43 | phosphatidylcholine + cholesterol | activity with apoB lipoprotein, overview | Mus musculus C57BL/6 | 1-acylglycerophosphocholine + cholesteryl ester | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.43 | LCAT | - |
Mus musculus |
2.3.1.43 | lecithin-cholesterol acyltransferase | - |
Mus musculus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.3.1.43 | 37 | - |
assay at | Mus musculus |