EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.7.14 | AMP-activated kinase | - |
Homo sapiens | |
2.7.7.14 | AMP-activated kinase | - |
Rattus norvegicus | |
2.7.7.14 | AMP-activated kinase | - |
Mus musculus | |
2.7.7.14 | additional information | does not require the presence of exogenous lipids for optimal activity | Homo sapiens | |
2.7.7.14 | additional information | does not require the presence of exogenous lipids for optimal activity | Rattus norvegicus | |
2.7.7.14 | additional information | does not require the presence of exogenous lipids for optimal activity | Mus musculus | |
2.7.7.14 | paramethoxyamphetamine | stimulates activity | Homo sapiens | |
2.7.7.14 | paramethoxyamphetamine | stimulates activity | Rattus norvegicus | |
2.7.7.14 | paramethoxyamphetamine | stimulates activity | Mus musculus |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.7.14 | - |
Homo sapiens |
2.7.7.14 | - |
Rattus norvegicus |
2.7.7.14 | - |
Saccharomyces cerevisiae |
2.7.7.14 | - |
Mus musculus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.7.14 | aminoimidazole-4-carboxamide | downregulates Pcyt2 activity | Homo sapiens | |
2.7.7.14 | aminoimidazole-4-carboxamide | downregulates Pcyt2 activity | Mus musculus | |
2.7.7.14 | aminoimidazole-4-carboxamide | downregulates Pcyt2 activity | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.7.14 | 0.053 | - |
Ethanolamine phosphate | - |
Rattus norvegicus | |
2.7.7.14 | 0.065 | - |
CTP | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.7.7.14 | cytosol | - |
Homo sapiens | 5829 | - |
2.7.7.14 | cytosol | - |
Rattus norvegicus | 5829 | - |
2.7.7.14 | cytosol | - |
Mus musculus | 5829 | - |
2.7.7.14 | membrane | associated with the membranes of the rough endoplasmic reticulum | Homo sapiens | 16020 | - |
2.7.7.14 | membrane | associated with the membranes of the rough endoplasmic reticulum | Rattus norvegicus | 16020 | - |
2.7.7.14 | membrane | associated with the membranes of the rough endoplasmic reticulum | Mus musculus | 16020 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.7.14 | 50000 | - |
SDS-PAGE | Homo sapiens |
2.7.7.14 | 50000 | - |
SDS-PAGE | Rattus norvegicus |
2.7.7.14 | 50000 | - |
SDS-PAGE | Mus musculus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.7.14 | Homo sapiens | - |
- |
- |
2.7.7.14 | Mus musculus | Q922E4 | - |
- |
2.7.7.14 | Rattus norvegicus | - |
- |
- |
2.7.7.14 | Saccharomyces cerevisiae | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.7.14 | - |
Homo sapiens |
2.7.7.14 | - |
Rattus norvegicus |
2.7.7.14 | - |
Saccharomyces cerevisiae |
2.7.7.14 | - |
Mus musculus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.7.14 | adipocyte | - |
Homo sapiens | - |
2.7.7.14 | adipocyte | - |
Mus musculus | - |
2.7.7.14 | adipocyte | high Pcyt2 mRNA content. Negligible amount of Pcyt2beta mRNA, high amount of Pcyt2alpha mRNA | Mus musculus | - |
2.7.7.14 | brain | low Pcyt2 mRNA content | Mus musculus | - |
2.7.7.14 | heart | - |
Homo sapiens | - |
2.7.7.14 | heart | - |
Mus musculus | - |
2.7.7.14 | heart | very low level of Pcyt2alpha | Homo sapiens | - |
2.7.7.14 | kidney | - |
Homo sapiens | - |
2.7.7.14 | kidney | - |
Mus musculus | - |
2.7.7.14 | kidney | negligible amount of Pcyt2beta mRNA, high amount of Pcyt2alpha mRNA | Mus musculus | - |
2.7.7.14 | liver | - |
Homo sapiens | - |
2.7.7.14 | liver | - |
Rattus norvegicus | - |
2.7.7.14 | liver | - |
Mus musculus | - |
2.7.7.14 | liver | low Pcyt2 mRNA content. Negligible amount of Pcyt2beta mRNA, high amount of Pcyt2alpha mRNA | Mus musculus | - |
2.7.7.14 | liver | Pcyt2 stays constant throughout the rat adult stage | Rattus norvegicus | - |
2.7.7.14 | additional information | Pcyt2 mRNA is barely detected in human kidney | Homo sapiens | - |
2.7.7.14 | skeletal muscle | low Pcyt2 mRNA content | Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.14 | CTP + ethanolamine phosphate | - |
Homo sapiens | diphosphate + CDP-ethanolamine | - |
? | |
2.7.7.14 | CTP + ethanolamine phosphate | - |
Rattus norvegicus | diphosphate + CDP-ethanolamine | - |
? | |
2.7.7.14 | CTP + ethanolamine phosphate | - |
Saccharomyces cerevisiae | diphosphate + CDP-ethanolamine | - |
? | |
2.7.7.14 | CTP + ethanolamine phosphate | - |
Mus musculus | diphosphate + CDP-ethanolamine | - |
? | |
2.7.7.14 | additional information | uses N-methylated derivatives of ethanolamine phosphate less efficiently and does not react with phosphocholine | Homo sapiens | ? | - |
? | |
2.7.7.14 | additional information | uses N-methylated derivatives of ethanolamine phosphate less efficiently and does not react with phosphocholine | Rattus norvegicus | ? | - |
? | |
2.7.7.14 | additional information | uses N-methylated derivatives of ethanolamine phosphate less efficiently and does not react with phosphocholine | Mus musculus | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.7.7.14 | dimer | - |
Homo sapiens |
2.7.7.14 | dimer | - |
Rattus norvegicus |
2.7.7.14 | dimer | - |
Mus musculus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.7.14 | CTP:phosphoethanolamine cytidylyltransferase | - |
Homo sapiens |
2.7.7.14 | CTP:phosphoethanolamine cytidylyltransferase | - |
Rattus norvegicus |
2.7.7.14 | CTP:phosphoethanolamine cytidylyltransferase | - |
Saccharomyces cerevisiae |
2.7.7.14 | CTP:phosphoethanolamine cytidylyltransferase | - |
Mus musculus |
2.7.7.14 | Pcyt2 | - |
Homo sapiens |
2.7.7.14 | Pcyt2 | - |
Rattus norvegicus |
2.7.7.14 | Pcyt2 | - |
Saccharomyces cerevisiae |
2.7.7.14 | Pcyt2 | - |
Mus musculus |
2.7.7.14 | Pcyt2alpha | longer variant of Pcyt2 | Homo sapiens |
2.7.7.14 | Pcyt2alpha | longer variant of Pcyt2 | Mus musculus |
2.7.7.14 | Pcyt2beta | shorter variant of Pcyt2 | Homo sapiens |
2.7.7.14 | Pcyt2beta | shorter variant of Pcyt2 | Mus musculus |