Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Mortimer, M.; Jaerving, R.; Brash, AA.R.; Samel, N.; Jaerving, I.
    Identification and characterization of an arachidonate 11R-lipoxygenase (2006), Arch. Biochem. Biophys., 445, 147-155.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.13.11.31 expressed in Escherichia coli BL21(DE3) cells Gersemia fruticosa

General Stability

EC Number General Stability Organism
1.13.11.31 the enzyme shows higher activity in 50 mM CAPS buffer (pH 10-11) and glycine buffer (pH 8.5-10.5) than in 50 mM Tris-HCl (pH 7-9) Gersemia fruticosa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.13.11.31 membrane
-
 Gersemia fruticosa 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.13.11.31 Ca2+ 10 mM, required for activity Gersemia fruticosa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.13.11.31 77000
-
 SDS-PAGE Gersemia fruticosa

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.31 Gersemia fruticosa
-
 soft coral
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.31 11,14,17-eicosatrienoic acid + O2 poor substrate Gersemia fruticosa ?
-
 ?
1.13.11.31 adrenic acid + O2
-
 Gersemia fruticosa ?
-
 ?
1.13.11.31 arachidonate + O2
-
 Gersemia fruticosa (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
-
 ?
1.13.11.31 dihomo-gamma linolenic acid + O2
-
 Gersemia fruticosa ?
-
 ?
1.13.11.31 docosahexaenoic acid + O2
-
 Gersemia fruticosa 14-hydroxydocosahexaenoic acid
-
 ?
1.13.11.31 eicosapentaenoic acid + O2
-
 Gersemia fruticosa 12-hydroxyeicosapentaenoic acid
-
 ?
1.13.11.31 gamma linolenic acid + O2 poor substrate Gersemia fruticosa 10-hydroxy-octadeca-(6Z,8E,12Z)-trienoic acid
-
 ?
1.13.11.31 linolenic acid + O2 poor substrate Gersemia fruticosa ?
-
 ?
1.13.11.31 additional information no reaction with mead acid and methyl esters of linolenic acid and arachidonate Gersemia fruticosa ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.13.11.31 11R-lipoxygenase
-
 Gersemia fruticosa
1.13.11.31 11R-LOX
-
 Gersemia fruticosa

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
1.13.11.31 5 15
-
 Gersemia fruticosa

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.13.11.31 25
-
 significant activity decrease above 25°C Gersemia fruticosa

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.13.11.31 7.5 11
-
 Gersemia fruticosa