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Literature summary extracted from

  • Mason, K.E.; Stofan, D.A.; Szweda, L.I.
    Inhibition of very long chain acyl-CoA dehydrogenase during cardiac ischemia (2005), Arch. Biochem. Biophys., 437, 138-143.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.3.8.8 Triton X-100 restores activity during ischemia Rattus norvegicus

Application

EC Number Application Comment Organism
1.3.8.8 medicine VLCAD represents a likely site for the modulation of substrate utilization during myocardial ischemia Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.8.8 mitochondrion
-
 Rattus norvegicus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.3.8.8 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.8.8 heart activity declines 34% during 30 min of ischemia Rattus norvegicus
-
1.3.8.8 myocardium
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.8.8 octanoyl-CoA + acceptor
-
 Rattus norvegicus 2-octenoyl-CoA + reduced acceptor
-
 ?
1.3.8.8 palmitoyl-CoA + electron-transfer flavoprotein
-
 Rattus norvegicus (2E)-2-hexadecenoyl-CoA + reduced electron-transfer flavoprotein
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.8.8 VLCAD
-
 Rattus norvegicus