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Literature summary extracted from
- Fluoromorphic Substrates for fatty acid metabolism: Highly sensitive probes for mammalian medium-chain acyl-CoA dehydrogenase (2006), Angew. Chem., 45, 637-642.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 1.3.8.7 | additional information | development of fluorogenic and fluoromorphic probes for the enzyme as indicators for selective and sensetive detection of MCAD activity in tissue homogenates | Rattus norvegicus |
| 1.3.8.7 | additional information | development of fluorogenic and fluoromorphic probes for the enzyme as indicators for selective and sensetive detection of MCAD activity in tissue homogenates | Sus scrofa |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.3.8.7 | 0.0023 | - |
octanoyl-CoA | - |
Sus scrofa |  |
| 1.3.8.7 | 0.004 | - |
octanoyl-CoA | - |
Rattus norvegicus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.3.8.7 | Rattus norvegicus | - |
- |
- |
| 1.3.8.7 | Sus scrofa | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.3.8.7 | - |
Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.3.8.7 | liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.3.8.7 | additional information | acts on a wide range of chain lengths (C16-C4) | Rattus norvegicus | ? | - |
? | |
| 1.3.8.7 | additional information | acts on a wide range of chain lengths (C16-C4) | Sus scrofa | ? | - |
? | |
| 1.3.8.7 | octanoyl-CoA + acceptor | - |
Rattus norvegicus | 2-octenoyl-CoA + reduced acceptor | - |
? | |
| 1.3.8.7 | octanoyl-CoA + acceptor | - |
Sus scrofa | 2-octenoyl-CoA + reduced acceptor | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.3.8.7 | general ACAD | - |
Rattus norvegicus |
| 1.3.8.7 | general ACAD | - |
Sus scrofa |
| 1.3.8.7 | MCAD | - |
Rattus norvegicus |
| 1.3.8.7 | MCAD | - |
Sus scrofa |
| 1.3.8.7 | medium-chain acyl-CoA dehydrogenase | - |
Rattus norvegicus |
| 1.3.8.7 | medium-chain acyl-CoA dehydrogenase | - |
Sus scrofa |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.3.8.7 | 19.6 | - |
octanoyl-CoA | - |
Sus scrofa | |
| 1.3.8.7 | 35.7 | - |
octanoyl-CoA | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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