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Literature summary extracted from
- Long-chain acyl-CoA hydrolase in the brain (2005), Amino Acids, 28, 273-278.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.3.8.8 | peroxisome proliferator | - |
Rattus norvegicus |
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 1.3.8.8 | additional information | CTE-II expression is induced during embryogenesis in association with neuronal differentiation, and persists after terminal differentiation in neurons at postnatal stages, resulting in constitutive high expression in the adult brain in a neuron-specific manner | Mus musculus |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.3.8.8 | - |
Mus musculus |
| 1.3.8.8 | - |
Homo sapiens |
| 1.3.8.8 | - |
Rattus norvegicus |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.3.8.8 | cytosol | CTE-II | Mus musculus | 5829 | - |
| 1.3.8.8 | cytosol | CTE-II | Homo sapiens | 5829 | - |
| 1.3.8.8 | cytosol | CTE-II | Rattus norvegicus | 5829 | - |
| 1.3.8.8 | mitochondrion | MTE-II | Mus musculus | 5739 | - |
| 1.3.8.8 | mitochondrion | MTE-II | Homo sapiens | 5739 | - |
| 1.3.8.8 | mitochondrion | MTE-II | Rattus norvegicus | 5739 | - |
| 1.3.8.8 | nucleus | CTE-II | Homo sapiens | 5634 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.3.8.8 | 43000 | - |
x * 43000 | Mus musculus |
| 1.3.8.8 | 43000 | - |
x * 43000 | Homo sapiens |
| 1.3.8.8 | 110000 | - |
- |
Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.3.8.8 | Homo sapiens | - |
- |
- |
| 1.3.8.8 | Mus musculus | - |
- |
- |
| 1.3.8.8 | Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.3.8.8 | - |
Mus musculus |
| 1.3.8.8 | - |
Homo sapiens |
| 1.3.8.8 | - |
Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.3.8.8 | adult | - |
Mus musculus | - |
| 1.3.8.8 | brain | exclusive expression of isoform CTE-II | Mus musculus | - |
| 1.3.8.8 | brain | exclusive expression of isoform CTE-II | Homo sapiens | - |
| 1.3.8.8 | central nervous system | - |
Mus musculus | - |
| 1.3.8.8 | central nervous system | - |
Rattus norvegicus | - |
| 1.3.8.8 | embryo | - |
Mus musculus | - |
| 1.3.8.8 | liver | induction of CTE-II and MTE-II by peroxisome proliferators, phenomenon specific to rats | Rattus norvegicus | - |
| 1.3.8.8 | neuron | - |
Mus musculus | - |
| 1.3.8.8 | neuron | - |
Homo sapiens | - |
| 1.3.8.8 | neuron | - |
Rattus norvegicus | - |
| 1.3.8.8 | peripheral nervous system | - |
Mus musculus | - |
| 1.3.8.8 | peripheral nervous system | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.3.8.8 | additional information | CTE-II highly specific for the hydrolysis of acyl-CoAs | Homo sapiens | ? | - |
? |  |
| 1.3.8.8 | additional information | hydrolysis of acyl-CoAs | Mus musculus | ? | - |
? | |
| 1.3.8.8 | additional information | hydrolysis of acyl-CoAs | Rattus norvegicus | ? | - |
? | |
| 1.3.8.8 | oleoyl-CoA + acceptor | - |
Homo sapiens | 2,9-octadecadienoyl-CoA + reduced acceptor | - |
? | |
| 1.3.8.8 | oleoyl-CoA + acceptor | - |
Rattus norvegicus | 2,9-octadecadienoyl-CoA + reduced acceptor | - |
? | |
| 1.3.8.8 | palmitoyl-CoA + electron-transfer flavoprotein | - |
Mus musculus | (2E)-2-hexadecenoyl-CoA + reduced electron-transfer flavoprotein | - |
? | |
| 1.3.8.8 | palmitoyl-CoA + electron-transfer flavoprotein | - |
Homo sapiens | (2E)-2-hexadecenoyl-CoA + reduced electron-transfer flavoprotein | - |
? | |
| 1.3.8.8 | palmitoyl-CoA + electron-transfer flavoprotein | - |
Rattus norvegicus | (2E)-2-hexadecenoyl-CoA + reduced electron-transfer flavoprotein | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.3.8.8 | ? | x * 43000 | Mus musculus |
| 1.3.8.8 | ? | x * 43000 | Homo sapiens |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.3.8.8 | BACH | - |
Mus musculus |
| 1.3.8.8 | BACH | - |
Homo sapiens |
| 1.3.8.8 | BACH | - |
Rattus norvegicus |
| 1.3.8.8 | CTE-II | - |
Mus musculus |
| 1.3.8.8 | CTE-II | - |
Homo sapiens |
| 1.3.8.8 | CTE-II | - |
Rattus norvegicus |
| 1.3.8.8 | long-chain acyl-CoA hydrolase | - |
Mus musculus |
| 1.3.8.8 | long-chain acyl-CoA hydrolase | - |
Homo sapiens |
| 1.3.8.8 | long-chain acyl-CoA hydrolase | - |
Rattus norvegicus |
| 1.3.8.8 | More | see also EC 3.1.2.2, palmitoyl-CoA hydrolase | Mus musculus |
| 1.3.8.8 | More | see also EC 3.1.2.2, palmitoyl-CoA hydrolase | Homo sapiens |
| 1.3.8.8 | More | see also EC 3.1.2.2, palmitoyl-CoA hydrolase | Rattus norvegicus |
| 1.3.8.8 | MTE-II | - |
Mus musculus |
| 1.3.8.8 | MTE-II | - |
Homo sapiens |
| 1.3.8.8 | MTE-II | - |
Rattus norvegicus |
| 1.3.8.8 | type-II acyl-CoA thioesterase | - |
Mus musculus |
| 1.3.8.8 | type-II acyl-CoA thioesterase | - |
Homo sapiens |
| 1.3.8.8 | type-II acyl-CoA thioesterase | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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