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Literature summary extracted from

  • Rajaram, V.; Prasad, K.; Ratna Prasuna, P.; Ramachandra, N.; Bharath, S.R.; Savithri, H.S.; Murthy, M.R.
    Cloning, purification, crystallization and preliminary X-ray crystallographic analysis of the biosynthetic N-acetylornithine aminotransferases from Salmonella typhimurium and Escherichia coli (2006), Acta Crystallogr. Sect. F, 62, 980-983.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.6.1.11 expressed in Escherichia coli Salmonella enterica subsp. enterica serovar Typhimurium
2.6.1.11 expressed in Escherichia coli Escherichia coli

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.6.1.11 hanging drop vapour diffusion in the presence of 1 mM 5-amino-1,3-cyclohexadienylcarboxylic acid Salmonella enterica subsp. enterica serovar Typhimurium
2.6.1.11 hanging drop vapour diffusion in the presence of 1 mM 5-amino-1,3-cyclohexadienylcarboxylic acid Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.11 5-amino-1,3-cyclohexadienylcarboxylic acid potent inhibitor Escherichia coli
2.6.1.11 5-amino-1,3-cyclohexadienylcarboxylic acid potent inhibitor Salmonella enterica subsp. enterica serovar Typhimurium

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.11 Escherichia coli
-
-
-
2.6.1.11 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.6.1.11 Ni-NTA affinity column chromatography Salmonella enterica subsp. enterica serovar Typhimurium
2.6.1.11 Ni-NTA affinity column chromatography Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.11 N-acetyl-L-glutamic gamma-semialdehyde + L-glutamate
-
 Salmonella enterica subsp. enterica serovar Typhimurium N2-acetyl-L-ornithine + 2-oxoglutarate
-
 ?
2.6.1.11 N-acetyl-L-glutamic gamma-semialdehyde + L-glutamate
-
 Escherichia coli N2-acetyl-L-ornithine + 2-oxoglutarate
-
 ?
2.6.1.11 N-succinyl-2-amino-6-oxopimelate + L-glutamate
-
 Escherichia coli N2-succinyl-1,6-diaminopimelate + 2-oxoglutarate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.6.1.11 ACOAT
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.6.1.11 ACOAT
-
 Escherichia coli
2.6.1.11 N-acetylornithine aminotransferase
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.6.1.11 N-acetylornithine aminotransferase
-
 Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.11 pyridoxal 5'-phosphate dependent Salmonella enterica subsp. enterica serovar Typhimurium
2.6.1.11 pyridoxal 5'-phosphate dependent Escherichia coli