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Literature summary extracted from

  • Natarajan, P.; Wang, J.; Hua, Z.; Graham, T.R.
    Drs2p-coupled aminophospholipid translocase activity in yeast Golgi membranes and relationship to in vivo function (2004), Proc. Natl. Acad. Sci. USA, 101, 10614-10619.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.6.2.1 protein Drs2p coupled to the enzyme, required for the translocation of phospholipids from the luminal leaflet of the membrane to the cytosolic leaflet in the trans-Golgi network, overview Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.6.2.1 Golgi membrane
-
Saccharomyces cerevisiae 139
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
7.6.2.1 Mg2+
-
Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.6.2.1 ATP + H2O + phosphatidylethanolamine/out Saccharomyces cerevisiae transport from the luminal leaflet of the membrane to the cytosolic leaflet ADP + phosphate + phosphatidylethanolamine/in
-
?
7.6.2.1 ATP + H2O + phosphatidylserine/out Saccharomyces cerevisiae transport from the luminal leaflet of the membrane to the cytosolic leaflet ADP + phosphate + phosphatidylserine/in
-
?

Organism

EC Number Organism UniProt Comment Textmining
7.6.2.1 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.6.2.1 ATP + H2O + phosphatidylethanolamine/out transport from the luminal leaflet of the membrane to the cytosolic leaflet Saccharomyces cerevisiae ADP + phosphate + phosphatidylethanolamine/in
-
?
7.6.2.1 ATP + H2O + phosphatidylethanolamine/out 7-nitro-2-1,3-benzoxadiazol-4-yl-fluorescent-labeled substrate, transport from the luminal leaflet of the membrane to the cytosolic leaflet Saccharomyces cerevisiae ADP + phosphate + phosphatidylethanolamine/in
-
?
7.6.2.1 ATP + H2O + phosphatidylserine/out transport from the luminal leaflet of the membrane to the cytosolic leaflet Saccharomyces cerevisiae ADP + phosphate + phosphatidylserine/in
-
?
7.6.2.1 ATP + H2O + phosphatidylserine/out 7-nitro-2-1,3-benzoxadiazol-4-yl-fluorescent-labeled substrate, transport from the luminal leaflet of the membrane to the cytosolic leaflet Saccharomyces cerevisiae ADP + phosphate + phosphatidylserine/in
-
?

Synonyms

EC Number Synonyms Comment Organism
7.6.2.1 aminophospholipid translocase
-
Saccharomyces cerevisiae
7.6.2.1 APLT
-
Saccharomyces cerevisiae