EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.42 | Cd2+ | coadministration with oxalomalate results in inhibition of enzyme and glutaredoxin and enhanced susceptibility to apoptosis | Mus musculus | |
1.1.1.42 | Cd2+ | binds to C379 of enzyme, resulting in loss of activity and structural alterations. Loss of glutaredoxin activity in cells treated with Cd2+ is more pronounced when cells are transfected with enzyme antisense cDNA | Sus scrofa | |
1.1.1.42 | Oxalomalate | competitive, coadministration with CD2+ results in inhibition of enzyme and glutaredoxin and enhanced susceptibility to apoptosis | Mus musculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.1.1.42 | mitochondrion | - |
Mus musculus | 5739 | - |
1.1.1.42 | mitochondrion | - |
Sus scrofa | 5739 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.42 | Mus musculus | - |
- |
- |
1.1.1.42 | Sus scrofa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.42 | heart | - |
Mus musculus | - |
1.1.1.42 | heart | - |
Sus scrofa | - |