BRENDA - Enzyme Database

Raman evidence for product binding to the enzyme W137F 4-chlorobenzoyl-CoA dehalogenase in two conformational states

Dong, J.; Luo, L.; Dunaway-Mariano, D.; Carey, P.R.; J. Raman Spectros. 36, 320-325 (2005)
No PubMed abstract available

Data extracted from this reference:

Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.8.1.7
Pseudomonas sp.
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.8.1.7
4-chlorobenzoyl-CoA + H2O
-
670022
Pseudomonas sp.
4-hydroxybenzoyl-CoA + chloride
the variant W137A binds the product 4-hydroxybenzoyl in two conformational states in the active site. In these two forms the 4-hydroxybenzoyl moiety is experiencing modest and very strong electron electron polarizing environments. The two forms may be interconverted by varying the temperature
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.8.1.7
4-chlorobenzoyl-CoA + H2O
-
670022
Pseudomonas sp.
4-hydroxybenzoyl-CoA + chloride
the variant W137A binds the product 4-hydroxybenzoyl in two conformational states in the active site. In these two forms the 4-hydroxybenzoyl moiety is experiencing modest and very strong electron electron polarizing environments. The two forms may be interconverted by varying the temperature
-
-
?