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Literature summary extracted from

  • Ylianttila, M.S.; Pursiainen, N.V.; Haapalainen, A.M.; Juffer, A.H.; Poirier, Y.; Kalervo Hiltunen, J.; Glumoff, T.
    Crystal structure of yeast peroxisomal multifunctional enzyme: structural basis for substrate specificity of (3R)-hydroxyacyl-CoA dehydrogenase units (2006), J. Mol. Biol., 358, 1286-1295.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.36 expressed in Escherichia coli Candida tropicalis

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.1.1.36 hanging-drop vapour diffusion Candida tropicalis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.36 Candida tropicalis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.36 Resource S cation exchange chromatography and Superdex 200 HR 10/30 column chromatography Candida tropicalis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.36 (3R)-hydroxybutyryl-CoA + NAD+
-
 Candida tropicalis 3-oxobutylryl-CoA + NADH
-
 ?
1.1.1.36 (3R)-hydroxydecanoyl-CoA + NAD+
-
 Candida tropicalis 3-oxodecanoyl-CoA + NADH
-
 ?
1.1.1.36 acetoacetyl-CoA + NADH + H+
-
 Candida tropicalis L-3-hydroxybutyryl-CoA + NAD+
-
 ?

Subunits

EC Number Subunits Comment Organism
1.1.1.36 heterodimer residues 1-313 and 314-604 forming the dehydrogenase A and B units, respectively Candida tropicalis

Synonyms

EC Number Synonyms Comment Organism
1.1.1.36 (3R)-hydroxyacyl-CoA dehydrogenase
-
 Candida tropicalis