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Literature summary extracted from

  • Actis-Goretta, L.; Ottaviani, J.I.; Fraga, C.G.
    Inhibition of angiotensin converting enzyme activity by flavanol-rich foods (2006), J. Agric. Food Chem., 54, 229-234.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.15.1 (+)-catechin IC50: about 1.6 mM Oryctolagus cuniculus
3.4.15.1 (-)-epicatechin IC50: about 1.7 mM Oryctolagus cuniculus
3.4.15.1 caffeic acid IC50: about 1.7 mM Oryctolagus cuniculus
3.4.15.1 chlorogenic acid IC50: about 1.8 mM Oryctolagus cuniculus
3.4.15.1 epigallocatechin IC50: about 0.3 mM Oryctolagus cuniculus
3.4.15.1 flavanol flavanols either isolated or present in foods can inhibit enzyme activity Oryctolagus cuniculus
3.4.15.1 gallic acid IC50 : about 1.7 mM Oryctolagus cuniculus
3.4.15.1 kaempferol IC50: about 1.2 mM Oryctolagus cuniculus
3.4.15.1 quercetin IC50: about 2.0 mM Oryctolagus cuniculus
3.4.15.1 resveratrol IC50: about 1.6 mM Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.1 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.15.1 lung
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.15.1 hippuryl-His-Leu + H2O
-
 Oryctolagus cuniculus hippuric acid + His-Leu
-
 ?

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.4.15.1 0.3
-
 IC50: about 0.3 mM Oryctolagus cuniculus epigallocatechin
3.4.15.1 1.2
-
 IC50: about 1.2 mM Oryctolagus cuniculus kaempferol
3.4.15.1 1.6
-
 IC50: about 1.6 mM Oryctolagus cuniculus resveratrol
3.4.15.1 1.6
-
 IC50: about 1.6 mM Oryctolagus cuniculus (+)-catechin
3.4.15.1 1.7
-
 IC50 : about 1.7 mM Oryctolagus cuniculus gallic acid
3.4.15.1 1.7
-
 IC50: about 1.7 mM Oryctolagus cuniculus caffeic acid
3.4.15.1 1.7
-
 IC50: about 1.7 mM Oryctolagus cuniculus (-)-epicatechin
3.4.15.1 1.8
-
 IC50: about 1.8 mM Oryctolagus cuniculus chlorogenic acid
3.4.15.1 2
-
 IC50: about 2.0 mM Oryctolagus cuniculus quercetin