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Literature summary extracted from

  • Duffy, D.M.; Seachord, C.L.; Dozier, B.L.
    Microsomal prostaglandin E synthase-1 (mPGES-1) is the primary form of PGES expressed by the primate periovulatory follicle (2005), Hum. Reprod., 20, 1485-1492.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.3.99.3 cPGES, expression analysis Macaca fascicularis
5.3.99.3 expression analysis Homo sapiens
5.3.99.3 mPGES-1, expression analysis Macaca fascicularis
5.3.99.3 mPGES-2, expression analysis Macaca fascicularis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.3.99.3 cytosol
-
Macaca fascicularis 5829
-
5.3.99.3 microsome
-
Homo sapiens
-
-
5.3.99.3 microsome
-
Macaca fascicularis
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.3.99.3 Prostaglandin H2 Macaca fascicularis
-
Prostaglandin E2
-
?
5.3.99.3 Prostaglandin H2 Homo sapiens mPGES-1 is a gonadotropin-regulated enzyme Prostaglandin E2
-
?
5.3.99.3 Prostaglandin H2 Macaca fascicularis mPGES-1 is a gonadotropin-regulated enzyme Prostaglandin E2
-
?

Organism

EC Number Organism UniProt Comment Textmining
5.3.99.3 Homo sapiens
-
women undergoing treatment for infertility, isozymes mPGES-2, mPGES-1, and cPGES
-
5.3.99.3 Macaca fascicularis Q5DI74 mPGES-1; cynomologus macaque, adult female, isozyme mPGES-1
-
5.3.99.3 Macaca fascicularis Q6PWL5 cPGES; cynomologus macaque, adult female, isozyme cPGES
-
5.3.99.3 Macaca fascicularis Q9N0A4 mPGES-2, truncated form; cynomologus macaque, adult female, isozyme mPGES-2
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.3.99.3 corpus luteum from women undergoing treatment for infertility, expression of mPGES-2, mPGES-1, and cPGES Homo sapiens
-
5.3.99.3 granulosa cell low level of cPGES Macaca fascicularis
-
5.3.99.3 granulosa cell low level of mPGES-2 Macaca fascicularis
-
5.3.99.3 granulosa cell mPGES-1 Macaca fascicularis
-
5.3.99.3 mature ovarian follicle expression of the primary form of PGES, mPGES-1 Macaca fascicularis
-
5.3.99.3 additional information tissue distribution of isozme expression, overview Macaca fascicularis
-
5.3.99.3 additional information tissue distribution of isozyme expression, overview Macaca fascicularis
-
5.3.99.3 oocyte
-
Macaca fascicularis
-
5.3.99.3 ovary
-
Macaca fascicularis
-
5.3.99.3 theca cell mPGES-1 Macaca fascicularis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.99.3 Prostaglandin H2
-
Homo sapiens Prostaglandin E2
-
?
5.3.99.3 Prostaglandin H2
-
Macaca fascicularis Prostaglandin E2
-
?
5.3.99.3 Prostaglandin H2 mPGES-1 is a gonadotropin-regulated enzyme Homo sapiens Prostaglandin E2
-
?
5.3.99.3 Prostaglandin H2 mPGES-1 is a gonadotropin-regulated enzyme Macaca fascicularis Prostaglandin E2
-
?

Synonyms

EC Number Synonyms Comment Organism
5.3.99.3 CPGES
-
Homo sapiens
5.3.99.3 CPGES
-
Macaca fascicularis
5.3.99.3 cytosolic prostaglandin E(2) synthase
-
Macaca fascicularis
5.3.99.3 cytosolic prostaglandin E(2) synthase-2
-
Homo sapiens
5.3.99.3 microsomal prostaglandin E(2) synthase-1
-
Homo sapiens
5.3.99.3 microsomal prostaglandin E(2) synthase-1
-
Macaca fascicularis
5.3.99.3 microsomal prostaglandin E(2) synthase-2
-
Homo sapiens
5.3.99.3 microsomal prostaglandin E(2) synthase-2
-
Macaca fascicularis
5.3.99.3 mPGES-1
-
Homo sapiens
5.3.99.3 mPGES-1
-
Macaca fascicularis
5.3.99.3 mPGES-2
-
Homo sapiens
5.3.99.3 mPGES-2
-
Macaca fascicularis