Any feedback?
Literature summary extracted from
- Oligopeptidase F (2004), Handbook of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press, 1, 369-370.
No PubMed abstract available
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Staphylococcus aureus |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Chlamydia trachomatis |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Mycoplasma genitalium |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Bacillus subtilis |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Streptococcus pneumoniae |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Streptococcus pyogenes |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Staphylococcus epidermidis |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Fusobacterium nucleatum |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Clostridium perfringens |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Streptococcus agalactiae |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Ureaplasma urealyticum |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Caldicellulosiruptor saccharolyticus |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Streptococcus mutans |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Mycoplasma pneumoniae |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Deinococcus radiodurans |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Listeria monocytogenes |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Borreliella burgdorferi |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Halobacterium sp. |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Chlamydia muridarum |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Chlamydia pneumoniae |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Mycoplasma capricolum |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Listeria innocua |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Caldanaerobacter subterraneus subsp. tengcongensis |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Mycoplasmopsis pulmonis |
| 3.4.24.B2 | additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Oceanobacillus iheyensis |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.4.24.B2 | overexpression in Bacillus subtilis | Bacillus subtilis |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.24.B2 | 1,10-phenanthroline | 1 mM inhibits | Lactococcus lactis |  |
| 3.4.24.B2 | EDTA | 1 mM inhibits, inhibition can be restored with Mn2+ and Co2+ | Lactococcus lactis | |
| 3.4.24.B2 | NaCl | 0.001 mM decreases enzyme activity by 25% | Lactococcus lactis | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.24.B2 | cytoplasm | - |
Lactococcus lactis | 5737 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.24.B2 | Zn2+ | zinc-binding motif HGXXH | Lactococcus lactis | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.B2 | 70000 | - |
sequence analysis | Lactococcus lactis |
| 3.4.24.B2 | 90000 | - |
gel filtration | Lactococcus lactis |
| 3.4.24.B2 | 98000 | - |
gel filtration | Lactococcus lactis |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.24.B2 | Bacillus anthracis | - |
- |
- |
| 3.4.24.B2 | Bacillus licheniformis | - |
- |
- |
| 3.4.24.B2 | Bacillus subtilis | - |
- |
- |
| 3.4.24.B2 | Borreliella burgdorferi | - |
- |
- |
| 3.4.24.B2 | Caldanaerobacter subterraneus subsp. tengcongensis | - |
- |
- |
| 3.4.24.B2 | Caldicellulosiruptor saccharolyticus | - |
- |
- |
| 3.4.24.B2 | Chlamydia muridarum | - |
- |
- |
| 3.4.24.B2 | Chlamydia pneumoniae | - |
- |
- |
| 3.4.24.B2 | Chlamydia trachomatis | - |
- |
- |
| 3.4.24.B2 | Clostridium perfringens | - |
- |
- |
| 3.4.24.B2 | Deinococcus radiodurans | - |
- |
- |
| 3.4.24.B2 | Fusobacterium nucleatum | - |
- |
- |
| 3.4.24.B2 | Halalkalibacterium halodurans | - |
- |
- |
| 3.4.24.B2 | Halobacterium sp. | - |
- |
- |
| 3.4.24.B2 | Halobacterium sp. NRC-1 | - |
- |
- |
| 3.4.24.B2 | Lactococcus lactis | - |
subsp. cremoris NCDO763 and subsp. lactis IL1403 | - |
| 3.4.24.B2 | Listeria innocua | - |
- |
- |
| 3.4.24.B2 | Listeria monocytogenes | - |
- |
- |
| 3.4.24.B2 | Mycoplasma capricolum | - |
- |
- |
| 3.4.24.B2 | Mycoplasma genitalium | - |
- |
- |
| 3.4.24.B2 | Mycoplasma pneumoniae | - |
- |
- |
| 3.4.24.B2 | Mycoplasmopsis pulmonis | - |
- |
- |
| 3.4.24.B2 | Oceanobacillus iheyensis | - |
- |
- |
| 3.4.24.B2 | Staphylococcus aureus | - |
- |
- |
| 3.4.24.B2 | Staphylococcus epidermidis | - |
- |
- |
| 3.4.24.B2 | Streptococcus agalactiae | - |
- |
- |
| 3.4.24.B2 | Streptococcus mutans | - |
- |
- |
| 3.4.24.B2 | Streptococcus pneumoniae | - |
- |
- |
| 3.4.24.B2 | Streptococcus pyogenes | - |
- |
- |
| 3.4.24.B2 | Streptococcus thermophilus | - |
- |
- |
| 3.4.24.B2 | Ureaplasma urealyticum | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.24.B2 | by chromatography | Lactococcus lactis |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.B2 | 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-D-Lys-(2,4-dinitrophenyl) + H2O | - |
Lactococcus lactis | ? | - |
? | |
| 3.4.24.B2 | bradykinin + H2O | best substrate among peptides | Lactococcus lactis | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.24.B2 | monomer | - |
Lactococcus lactis |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.24.B2 | alkaline endopeptidase | - |
Lactococcus lactis |
| 3.4.24.B2 | LEPI | - |
Lactococcus lactis |
| 3.4.24.B2 | PepF | - |
Staphylococcus aureus |
| 3.4.24.B2 | PepF | - |
Chlamydia trachomatis |
| 3.4.24.B2 | PepF | - |
Mycoplasma genitalium |
| 3.4.24.B2 | PepF | - |
Bacillus subtilis |
| 3.4.24.B2 | PepF | - |
Lactococcus lactis |
| 3.4.24.B2 | PepF | - |
Streptococcus pneumoniae |
| 3.4.24.B2 | PepF | - |
Streptococcus pyogenes |
| 3.4.24.B2 | PepF | - |
Staphylococcus epidermidis |
| 3.4.24.B2 | PepF | - |
Bacillus licheniformis |
| 3.4.24.B2 | PepF | - |
Streptococcus thermophilus |
| 3.4.24.B2 | PepF | - |
Fusobacterium nucleatum |
| 3.4.24.B2 | PepF | - |
Clostridium perfringens |
| 3.4.24.B2 | PepF | - |
Streptococcus agalactiae |
| 3.4.24.B2 | PepF | - |
Ureaplasma urealyticum |
| 3.4.24.B2 | PepF | - |
Caldicellulosiruptor saccharolyticus |
| 3.4.24.B2 | PepF | - |
Streptococcus mutans |
| 3.4.24.B2 | PepF | - |
Mycoplasma pneumoniae |
| 3.4.24.B2 | PepF | - |
Deinococcus radiodurans |
| 3.4.24.B2 | PepF | - |
Listeria monocytogenes |
| 3.4.24.B2 | PepF | - |
Borreliella burgdorferi |
| 3.4.24.B2 | PepF | - |
Halalkalibacterium halodurans |
| 3.4.24.B2 | PepF | - |
Halobacterium sp. |
| 3.4.24.B2 | PepF | - |
Chlamydia muridarum |
| 3.4.24.B2 | PepF | - |
Chlamydia pneumoniae |
| 3.4.24.B2 | PepF | - |
Bacillus anthracis |
| 3.4.24.B2 | PepF | - |
Mycoplasma capricolum |
| 3.4.24.B2 | PepF | - |
Listeria innocua |
| 3.4.24.B2 | PepF | - |
Caldanaerobacter subterraneus subsp. tengcongensis |
| 3.4.24.B2 | PepF | - |
Mycoplasmopsis pulmonis |
| 3.4.24.B2 | PepF | - |
Oceanobacillus iheyensis |
| 3.4.24.B2 | PepF1 | - |
Lactococcus lactis |
| 3.4.24.B2 | PepF2 | - |
Lactococcus lactis |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.B2 | 40 | - |
- |
Lactococcus lactis |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.B2 | 7 | 9 | - |
Lactococcus lactis |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
