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Literature summary extracted from

  • Tu, L.Q.; Wright, P.F.; Rix, C.J.; Ahokas, J.T.
    Is fluoroacetate-specific defluorinase a glutathione S-transferase? (2006), Comp. Biochem. Physiol. C, 143C, 59-66.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.8.1.3 1,2-epoxy-3-(p-nitrophenoxy)propane
-
 Rattus norvegicus
3.8.1.3 1-chloro-2,3-dinitrobenzene
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.8.1.3 3.8
-
 fluoroacetate 25°C Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.8.1.3 cytosol
-
 Rattus norvegicus 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.8.1.3 fluoroacetate + H2O Rattus norvegicus critical enzyme in the detoxication of fluoroacetate glycolate + fluoride
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.8.1.3 Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.8.1.3 fluoroacetate + H2O
-
 Rattus norvegicus glycolate + fluoride
-
 ?
3.8.1.3 fluoroacetate + H2O critical enzyme in the detoxication of fluoroacetate Rattus norvegicus glycolate + fluoride
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.8.1.3 fluoroacetate-specific defluorinase
-
 Rattus norvegicus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.8.1.3 5.61
-
 1-chloro-2,3-dinitrobenzene
-
 Rattus norvegicus
3.8.1.3 17.6
-
 1,2-epoxy-3-(p-nitrophenoxy)propane
-
 Rattus norvegicus