Literature summary extracted from

Deschamps, A.M.; Yarbrough, W.M.; Squires, C.E.; Allen, R.A.; McClister, D.M.; Dowdy, K.B.; McLean, J.E.; Mingoia, J.T.; Sample, J.A.; Mukherjee, R.; Spinale, F.G.
Trafficking of the membrane type-1 matrix metalloproteinase in ischemia and reperfusion: relation to interstitial membrane type-1 matrix metalloproteinase activity (2005), Circulation, 111, 1166-1174.

Application

EC Number	Application	Comment	Organism
3.4.24.80	medicine	mechanistic association between MT1-MMP levels and post-I/R remodeling, multiple targets for the interruption of augmented MT1-MMP activity and abundance with I/R	Sus scrofa

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.24.80	TIMP-3	during ischemia, loss of inhibitory control leading to increased MT1-MMP activity	Sus scrofa
3.4.24.80	TIMP-4	during ischemia, loss of inhibitory control leading to increased MT1-MMP activity	Sus scrofa

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.24.80	Sus scrofa	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.24.80	myocardium	ischemic and nonischemic remote myocardium	Sus scrofa	-

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.24.80	membrane type 1 matrix metalloproteinase	-	Sus scrofa
3.4.24.80	membrane type MMP-1	-	Sus scrofa
3.4.24.80	MT1-MMP	-	Sus scrofa

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Release 2023.1 (January 2023)