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Literature summary extracted from

  • Kim, H.Y.; Gladyshev, V.N.
    Alternative first exon splicing regulates subcellular distribution of methionine sulfoxide reductases (2006), BMC Mol. Biol., 7, 11.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.8.4.11 genomic structure, alternative splicing variants, overview Homo sapiens
1.8.4.11 genomic structure, alternative splicing variants, overview Drosophila melanogaster
1.8.4.11 genomic structure, alternative splicing variants, overview, expression of GFP-tagged and/or His-tagged mitochondrial and cytosolic MsrAs in CV-1 cells Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.4.11 cytosol
-
 Homo sapiens 5829
-
1.8.4.11 cytosol
-
 Drosophila melanogaster 5829
-
1.8.4.11 cytosol isozyme MsrA3 Homo sapiens 5829
-
1.8.4.11 cytosol splicing variant MsrA(S) Mus musculus 5829
-
1.8.4.11 mitochondrion
-
 Homo sapiens 5739
-
1.8.4.11 mitochondrion mitochondrial splicing variant MsrA Mus musculus 5739
-
1.8.4.11 additional information subcellular localization is regulated by alternative splicing, overview Homo sapiens
-
-
1.8.4.11 additional information subcellular localization is regulated by alternative splicing, overview Drosophila melanogaster
-
-
1.8.4.11 additional information subcellular localization is regulated by alternative splicing, overview Mus musculus
-
-
1.8.4.11 nucleus
-
 Homo sapiens 5634
-
1.8.4.11 nucleus splicing variant MsrA(S) Mus musculus 5634
-

Organism

EC Number Organism UniProt Comment Textmining
1.8.4.11 Drosophila melanogaster P08761 gene Eip71CD or Eip28/29; alternative splicing variants, overview
-
1.8.4.11 Homo sapiens
-
 alternative splicing variants, overview
-
1.8.4.11 Homo sapiens Q9UJ68 isozyme MsrA3; alternative splicing variants, overview
-
1.8.4.11 Mus musculus Q9D6Y7 alternative splicing variants, overview
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.4.11 brain
-
 Mus musculus
-
1.8.4.11 kidney
-
 Mus musculus
-
1.8.4.11 liver
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.4.11 L-methionine-(S)-S-oxide + thioredoxin stereospecific reduction Homo sapiens L-methionine + thioredoxin disulfide + H2O
-
 ?
1.8.4.11 L-methionine-(S)-S-oxide + thioredoxin stereospecific reduction Mus musculus L-methionine + thioredoxin disulfide + H2O
-
 ?
1.8.4.11 peptide-L-methionine-(S)-S-oxide + thioredoxin stereospecific reduction Drosophila melanogaster peptide-L-methionine + thioredoxin disulfide + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.4.11 ecdysone-induced protein 28/29 kDa
-
 Drosophila melanogaster
1.8.4.11 methionine sulfoxide reductase A
-
 Homo sapiens
1.8.4.11 methionine sulfoxide reductase A
-
 Drosophila melanogaster
1.8.4.11 methionine sulfoxide reductase A
-
 Mus musculus
1.8.4.11 MsrA
-
 Homo sapiens
1.8.4.11 MsrA
-
 Drosophila melanogaster
1.8.4.11 MsrA
-
 Mus musculus
1.8.4.11 peptide methionine sulfoxide reductase
-
 Drosophila melanogaster

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.4.11 thioredoxin
-
 Drosophila melanogaster