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Literature summary extracted from

  • Matheson, N.R.; Potempa, J.; Travis, J.
    Interaction of a novel form of Pseudomonas aeruginosa alkaline protease (aeruginolysin) with interleukin-6 and interleukin-8 (2006), Biol. Chem., 387, 911-915.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
3.4.24.40 additional information enzyme form bearing residues Leu-Lys at the N-terminus, in the absence of calcium far more efficient degradation of interleukins IL-6 and IL-8 than wild-type Pseudomonas aeruginosa

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.26 Pseudomonas aeruginosa
-
-
-
3.4.24.40 Pseudomonas aeruginosa
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.26 interleukin-6 + H2O complete digestion Pseudomonas aeruginosa ?
-
?
3.4.24.26 interleukin-8 + H2O rapid processing to a 72 amino acid form, further degradation is slow Pseudomonas aeruginosa ?
-
?
3.4.24.40 interleukin-6 + H2O complete digestion Pseudomonas aeruginosa ?
-
?
3.4.24.40 interleukin-8 + H2O rapid processing to a 72 amino acid form, further degradation is slow Pseudomonas aeruginosa ?
-
?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.26 aeruginolysin
-
Pseudomonas aeruginosa
3.4.24.40 aeruginolysin
-
Pseudomonas aeruginosa