EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
7.2.2.9 | glutaredoxin | is essential for ATPase function and catalysis either the reduction of intramolecular disulphide bonds or the deglutathionylation of the cysteine residues within the CxxC motifs to facilitate copper-binding for subsequent transport | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
7.2.2.9 | Homo sapiens | P35670 | - |
- |
7.2.2.9 | Homo sapiens | Q04656 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
7.2.2.9 | skin fibroblast | overexpressing ATP7A or ATP7B | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.2.2.9 | ATP + H2O + Cu2+/in | ATP7A and ATP7B are the key copper transporters that regulate copper homeostasis | Homo sapiens | ADP + phosphate + Cu2+/out | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
7.2.2.9 | ATP7A | - |
Homo sapiens |
7.2.2.9 | ATP7B | - |
Homo sapiens |