BRENDA - Enzyme Database show

Altered expression of COX-1, COX-2, and mPGES in rats with nephrogenic and central diabetes insipidus

Kotnik, P.; Nielsen, J.; Kwon, T.H.; Krzisnik, C.; Fr?kiaer, J.; Nielsen, S.; Am. J. Physiol. Renal Physiol. 288, F1053-F1068 (2005)

Data extracted from this reference:

Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
5.3.99.3
membrane
associated
Rattus norvegicus
16020
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.3
Prostaglandin H2
Rattus norvegicus
-
Prostaglandin E2
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.3
Rattus norvegicus
-
Wistar rats
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.3
kidney
mainly inner medulla, expression overview
Rattus norvegicus
-
5.3.99.3
additional information
the enzyme expression is altered in rats with nephrogenic and central diabetes insipidus, expression overview
Rattus norvegicus
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
5.3.99.3
additional information
-
measurement of urinary prostaglandin E2
Rattus norvegicus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.3
Prostaglandin H2
-
667165
Rattus norvegicus
Prostaglandin E2
-
-
-
?
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
5.3.99.3
membrane
associated
Rattus norvegicus
16020
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.3
Prostaglandin H2
Rattus norvegicus
-
Prostaglandin E2
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.3
kidney
mainly inner medulla, expression overview
Rattus norvegicus
-
5.3.99.3
additional information
the enzyme expression is altered in rats with nephrogenic and central diabetes insipidus, expression overview
Rattus norvegicus
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
5.3.99.3
additional information
-
measurement of urinary prostaglandin E2
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.3
Prostaglandin H2
-
667165
Rattus norvegicus
Prostaglandin E2
-
-
-
?