Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Jann, A.; Stalon, V.; Wauven, C.V.; Leisinger, T.; Haas, D.
    N-Succinylated intermediates in an arginine catabolic pathway of Pseudomonas aeruginosa (1986), Proc. Natl. Acad. Sci. USA, 83, 4937-4941.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.6.1.81 additional information arginine induces the enzymes of the entire pathway, while succinate and ammonium suppress them Pseudomonas aeruginosa

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.81 aminooxoacetic acid leads to accumulation of succinyl-L-ornithine in vivo Pseudomonas aeruginosa
2.6.1.81 additional information arginine induces the enzymes of the entire pathway, while succinate and ammonium suppress them Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.81 N2-succinyl-L-ornithine + 2-oxoglutarate Pseudomonas aeruginosa step in metabolic conversion of L-arginine into L-glutamate, pathway overview N-succinyl-L-glutamate 5-semialdehyde + L-glutamate
-
 ?
2.6.1.81 N2-succinyl-L-ornithine + 2-oxoglutarate Pseudomonas aeruginosa PAO step in metabolic conversion of L-arginine into L-glutamate, pathway overview N-succinyl-L-glutamate 5-semialdehyde + L-glutamate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.81 Pseudomonas aeruginosa
-
-
-
2.6.1.81 Pseudomonas aeruginosa PAO
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.81 N2-succinyl-L-ornithine + 2-oxoglutarate
-
 Pseudomonas aeruginosa N-succinyl-L-glutamate 5-semialdehyde + L-glutamate
-
 ?
2.6.1.81 N2-succinyl-L-ornithine + 2-oxoglutarate step in metabolic conversion of L-arginine into L-glutamate, pathway overview Pseudomonas aeruginosa N-succinyl-L-glutamate 5-semialdehyde + L-glutamate
-
 ?
2.6.1.81 N2-succinyl-L-ornithine + 2-oxoglutarate
-
 Pseudomonas aeruginosa PAO N-succinyl-L-glutamate 5-semialdehyde + L-glutamate
-
 ?
2.6.1.81 N2-succinyl-L-ornithine + 2-oxoglutarate step in metabolic conversion of L-arginine into L-glutamate, pathway overview Pseudomonas aeruginosa PAO N-succinyl-L-glutamate 5-semialdehyde + L-glutamate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.6.1.81 37
-
 assay at Pseudomonas aeruginosa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.6.1.81 7
-
 assay at Pseudomonas aeruginosa

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.81 pyridoxal 5'-phosphate
-
 Pseudomonas aeruginosa